478954-81-3

478954-81-3 structure

Name: Monobutyl phthalate-d4
Chemical Name: 2-butoxycarbonyl-3,4,5,6-tetradeuteriobenzoic acid
CAS Number: 478954-81-3
Molecular Formula: C₁₂H₁₄O₄
Molecular Weight: 222.23700
Catalog: Signaling Pathways Others Others
Create Date: 2018-03-22 08:00:00
Modify Date: 2023-01-04 12:25:29
Monobutyl phthalate-d4 is the deuterium labeled Monobutyl phthalate[1]. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant[2][3].

Name	2-butoxycarbonyl-3,4,5,6-tetradeuteriobenzoic acid
Synonyms	Mono-n-butyl Phthalate-d4 Phthalic Acid-d4 Butyl Ester MnBP-d4 Butyl Hydrogen Phthalate-d4 Monobutyl Phthalate-d4

Description	Monobutyl phthalate-d4 is the deuterium labeled Monobutyl phthalate[1]. Monobutyl phthalate, a major metabolite of dibutyl phthalate (DBP), possesses antiandrogenic effects. Monobutyl phthalate is an embryotoxicant[2][3].
Related Catalog	Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. van Dartel DA, et al. Early gene expression changes during embryonic stem cell differentiation into cardiomyocytes and their modulation by monobutyl phthalate. Reprod Toxicol. 2009 Apr;27(2):93-102. [3]. Ema M, et al. Antiandrogenic effects of dibutyl phthalate and its metabolite, monobutyl phthalate, in rats. Congenit Anom (Kyoto). 2002 Dec;42(4):297-308.