198284-23-0

198284-23-0 structure

Name: Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine
Chemical Name: (2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid
CAS Number: 198284-23-0
Molecular Formula: C₂₆H₃₄N₄O₆
Molecular Weight: 498.57100
Catalog: Signaling Pathways Metabolic Enzyme/Protease Angiotensin-converting Enzyme (ACE)
Create Date: 2017-12-24 17:17:48
Modify Date: 2024-01-12 19:45:00
Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is a blood pressure lowering peptide containing 4 amino acids. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is an angiotensin-converting Enzyme (ACE) inhibitor. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine can be used in research of high blood pressure[1].

Name	(2S)-2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid
Synonyms	L-Phenylalanine,L-tyrosylglycyl-L-leucyl

Description	Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is a blood pressure lowering peptide containing 4 amino acids. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine is an angiotensin-converting Enzyme (ACE) inhibitor. Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine can be used in research of high blood pressure[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
In Vivo	Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine (1-1000 μg/kg; s.c.) inhibits blood pressure in normotensive and spontaneously hypertensive rats[1]. Animal Model: Adult male SHR and WKY rats[1] Dosage: 1, 10, 100, and 1000 μg/kg Administration: Subcutaneous injection Result: Inhibited blood pressure in a dose-dependent manner.
References	[1]. Nurminen MN, et, al. α-Lactorphin lowers blood pressure measured by radiotelemetry in normotensive and spontaneously hypertensive rats. Life Sciences. 2000 Mar 10;66(16):1535-43.