34450-16-3

34450-16-3 structure

Name: N1-Acetylspermidine hydrochloride
Chemical Name: N1-acetylspermidine dihydrochloride
CAS Number: 34450-16-3
Molecular Formula: C₉H₂₃Cl₂N₃O
Molecular Weight: 223.74300
Create Date: 2016-02-28 02:11:44
Modify Date: 2024-01-05 19:55:40
N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamine. N1-acetylspermine is the substrate for the polyamine oxidase (PAO). N1-Acetylspermidine hydrochloride selectively elevates its level in human colorectal adenocarcinomas. N1-acetylspermidine shows cleavage efficiency at apurinic sites in DNA[1][2][3].

Name	N1-acetylspermidine dihydrochloride
Synonyms	Acetamide, N-[3-[(4-aminobutyl)amino]propyl]-, dihydrochloride N1-Acetylspermidine (hydrochloride)

Description	N1-Acetylspermidine hydrochloride is an acetyl derivative of polyamine. N1-acetylspermine is the substrate for the polyamine oxidase (PAO). N1-Acetylspermidine hydrochloride selectively elevates its level in human colorectal adenocarcinomas. N1-acetylspermidine shows cleavage efficiency at apurinic sites in DNA[1][2][3].
Related Catalog	Research Areas >> Cancer
References	[1]. Royo M, et al. Mechanistic studies of mouse polyamine oxidase with N1,N12-bisethylspermine as a substrate. Biochemistry. 2005 May 10;44(18):7079-84. [2]. Takenoshita S, et al. Selective elevation of the N1-acetylspermidine level in human colorectal adenocarcinomas. Cancer Res. 1984 Feb;44(2):845-7. [3]. Haukanes BI, et al. Action of spermidine, N1-acetylspermidine, and N8-acetylspermidine at apurinic sites in DNA.

Hazard Codes	Xi