Name | sb 297006 |
---|---|
Synonyms | n-benzoyl-4-nitroaniline ethyl ester |
Description | SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells. |
---|---|
Related Catalog | |
Target |
CCR3[1] |
In Vitro | SB297006 is a CCR3 antagonist, significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells (NPCs) at 100 μM[1]. |
Cell Assay | To evaluate CCR3 blocking, neural progenitor cells (NPCs) are incubated with the CCR3 antagonist SB297006 (100 μM) for 30 minutes and then stimulated with CCL11 (2 μg/mL). After 3 days of culture, NPCs are subjected to CCK-8 assays[1]. |
References |
Melting Point | 121 °C |
---|---|
Molecular Formula | C18H18N2O5 |
Molecular Weight | 342.34600 |
Exact Mass | 342.12200 |
PSA | 101.22000 |
LogP | 3.41310 |
Symbol |
![]() ![]() GHS07, GHS09 |
---|---|
Signal Word | Warning |
Hazard Statements | H302-H400 |
Precautionary Statements | P273 |
RIDADR | UN 3077 9 / PGIII |
Precursor 0 | |
---|---|
DownStream 1 | |