18828-58-5

18828-58-5 structure

Name: (±)-Propionylcarnitine chloride
Chemical Name: (+/-)-propionylcarnitine chloride
CAS Number: 18828-58-5
Molecular Formula: C₁₀H₂₀ClNO₄
Molecular Weight: 253.72300
Catalog: Research Areas Inflammation/Immunology
Create Date: 2016-12-07 23:40:15
Modify Date: 2024-01-05 22:26:28
Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation[1][2][3][4].

Name	(+/-)-propionylcarnitine chloride
Synonyms	(±)-Propionylcarnitine chloride O-Propionylcarnitinhydrochlorid

Description	Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation[1][2][3][4].
Related Catalog	Research Areas >> Inflammation/Immunology
In Vitro	Propionyl-DL-carnitine chloride shows protection to beta-thalassaemic erythrocytes from oxidative stress[1]. Propionyl-DL-carnitine chloride increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl camitine from pyruvate[2]. Propionyl-DL-carnitine chloride allows the endothelial cells to maintain their functionality and regulatory role on vessel activity for a longer time and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine formed by adenine nucleotide catabolism[4].
In Vivo	Propionyl-DL-carnitine chloride (2 mM/kg; p.o. once daily for 4 weeks) affects plasma and urine total carnitine concentrations of mice[3]. Animal Model: Adult age-matched male C57BL/6 mice[3] Dosage: 2 mM/kg Administration: Oral gavage; 2 mM/kg/day for 4 weeks Result: Increased plasma and urine total carnitine concentrations, but showed no effect on the skeletal muscle carnitine content of mice.