84633-33-0

84633-33-0 structure

Name: Asparanin A
Chemical Name: (25S)-5β-spirostan-3β-ol 3-O-β-D-glucopyranosyl-(1->2)-β-D-glucopyranoside
CAS Number: 84633-33-0
Molecular Formula: C₃₉H₆₄O₁₃
Molecular Weight: 740.91800
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2017-12-07 01:00:47
Modify Date: 2024-01-29 19:35:25
Asparanin A is an apoptosis inducer with anticancer activity. Asparanin A induces cell cycle arrest in the G0/G1 phase through mitochondria and PI3K/AKT signaling pathways, inhibiting cancer cell growth. Asparanin A also demonstrated in vivo efficacy in a mouse xenograft model of Ishikawa endometrial carcinoma, significantly inhibiting tumor growth[1].

Name	(25S)-5β-spirostan-3β-ol 3-O-β-D-glucopyranosyl-(1->2)-β-D-glucopyranoside
Synonyms	(25S)-5β-spirostan-3β-ol-3-O-β-D-glucopyranosyl-(1,2)-β-D-glucopyranoside asparanin A 3-O-[β-D-glucopyranosyl(1->2)-β-D-glucopyranosyl]-(25S)-5β-spirostan-3β-ol (25S)-5β-spirostan-3β-ol-3-O-β-D-glucopyranosyl(1->2)-β-D-glucopyranoside 3-O-β-D-glucopyranosyl-(1->2)-β-D-glucopyranosyl-5β(25S)-spirostan-3β-ol 25(S)-schidigera-saponin D5

Description	Asparanin A is an apoptosis inducer with anticancer activity. Asparanin A induces cell cycle arrest in the G0/G1 phase through mitochondria and PI3K/AKT signaling pathways, inhibiting cancer cell growth. Asparanin A also demonstrated in vivo efficacy in a mouse xenograft model of Ishikawa endometrial carcinoma, significantly inhibiting tumor growth[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Zhang F, et al. Asparanin A from Asparagus officinalis L. Induces G0/G1 Cell Cycle Arrest and Apoptosis in Human Endometrial Carcinoma Ishikawa Cells via Mitochondrial and PI3K/AKT Signaling Pathways. J Agric Food Chem. 2020 Jan 8;68(1):213-224..

Precursor 0
DownStream 2
126-19-2 50-99-7