Shanghai Nianxing Industrial Co., Ltd
China
Product Name: HO-PEG8-CH2CH2COOH
Price: Check
Purity: 97.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Hydroxy-PEG8-acid
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

937188-60-8

937188-60-8 structure

937188-60-8 structure

Name: HO-PEG8-CH2CH2COOH
Chemical Name: Propanoic acid, 3-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]
CAS Number: 937188-60-8
Molecular Formula: C₁₉H₃₈O₁₁
Molecular Weight: 442.49800
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-05-29 04:50:46
Modify Date: 2024-01-09 18:50:21
HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propanoic acid, 3-[(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]
Synonyms	HO-PEG8-CH2CH2COOH Alpha-hydroxy-ω-propionic acid octaethylene glycol

Description	HO-PEG8-CH2CH2COOH (Hydroxy-PEG8-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density	1.148±0.06 g/cm3 (20 °C, 760 mmHg)
Boiling Point	554.3±50.0 °C (760 mmHg)
Molecular Formula	C₁₉H₃₈O₁₁
Molecular Weight	442.49800
Exact Mass	442.24100
PSA	131.37000

Hazard Codes	Xi

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