891198-38-2

891198-38-2 structure

Name: Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 trifluoroacetate salt
Chemical Name: L-Alaninamide, 1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]
CAS Number: 891198-38-2
Molecular Formula: C₅₃H₇₀N₁₂O₂₀
Molecular Weight: 1195.19000
Catalog: Research Areas Cancer
Create Date: 2016-05-15 13:02:08
Modify Date: 2025-08-20 18:37:08
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is highly selective substrate for matrix metalloproteases 12 (MMP12) substrate with a kcat/Km value of 1.85*105 M-1s-1, and poor substrate of other MMPs with the exception of MMP13 (kcat/Km = 0.53*105 M-1s-1) and MMP9 (0.33*105 M-1s-1)[1].

Name	L-Alaninamide, 1-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucylglycyl-L-leucyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-3-[(2,4-dinitrophenyl)amino]
Synonyms	Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 390 MMP FRET SUBSTRATE (V)

Description	Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is highly selective substrate for matrix metalloproteases 12 (MMP12) substrate with a kcat/Km value of 1.85105 M-1s-1, and poor substrate of other MMPs with the exception of MMP13 (kcat/Km = 0.53105 M-1s-1) and MMP9 (0.33*105 M-1s-1)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	others
References	[1]. Sarah Bregant, et al. Detection of matrix metalloproteinase active forms in complex proteomes: evaluation of affinity versus photoaffinity capture. J Proteome Res. 2009 May;8(5):2484-94.