13276-43-2

13276-43-2 structure

Name: 2-chloroinosine
Chemical Name: 2-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
CAS Number: 13276-43-2
Molecular Formula: C₁₀H₁₁ClN₄O₅
Molecular Weight: 302.67
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-04-23 08:00:00
Modify Date: 2024-01-09 12:29:45
2-Chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Synonyms	2-Chloroinosine 2-Chlor-inosin

Description	2-Chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

146-77-0

13276-43-2

Literature: Chemical Research in Toxicology, , vol. 11, # 12 p. 1453 - 1459

26550-86-7

13276-43-2

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 21 p. 2937 - 2941

118-00-3

80394-72-5

13276-43-2

146-80-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 21 p. 2937 - 2941

Precursor 2
146-77-0 118-00-3
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