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13276-43-2

13276-43-2 structure
13276-43-2 structure
  • Name: 2-chloroinosine
  • Chemical Name: 2-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
  • CAS Number: 13276-43-2
  • Molecular Formula: C10H11ClN4O5
  • Molecular Weight: 302.67
  • Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
  • Create Date: 2018-04-23 08:00:00
  • Modify Date: 2024-01-09 12:29:45
  • 2-Chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 2-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Synonyms 2-Chloroinosine
2-Chlor-inosin
Description 2-Chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 2.194 g/cm3
Melting Point 141-143ºC (dec.)
Molecular Formula C10H11ClN4O5
Molecular Weight 302.67
Exact Mass 302.04200
PSA 133.49000
Storage condition -20°C Freezer

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13276-43-2 structure

13276-43-2

Literature: Chemical Research in Toxicology, , vol. 11, # 12 p. 1453 - 1459

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13276-43-2 structure

13276-43-2

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 21 p. 2937 - 2941

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13276-43-2 structure

13276-43-2

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 21 p. 2937 - 2941
Precursor  2

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