2-chloroinosine

Modify Date: 2024-01-09 12:29:45

2-chloroinosine Structure
2-chloroinosine structure
Common Name 2-chloroinosine
CAS Number 13276-43-2 Molecular Weight 302.67
Density 2.194 g/cm3 Boiling Point N/A
Molecular Formula C10H11ClN4O5 Melting Point 141-143ºC (dec.)
MSDS N/A Flash Point N/A

 Use of 2-chloroinosine


2-Chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-chloro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Synonym More Synonyms

 2-chloroinosine Biological Activity

Description 2-Chloroinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.194 g/cm3
Melting Point 141-143ºC (dec.)
Molecular Formula C10H11ClN4O5
Molecular Weight 302.67
Exact Mass 302.04200
PSA 133.49000
Storage condition -20°C Freezer

 Synthetic Route

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2-chloroinosine Structure

2-chloroinosine

CAS#:13276-43-2

Literature: Chemical Research in Toxicology, , vol. 11, # 12 p. 1453 - 1459

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2-chloroinosine Structure

2-chloroinosine

CAS#:13276-43-2

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 21 p. 2937 - 2941

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2-chloroinosine Structure

2-chloroinosine

CAS#:13276-43-2

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 21 p. 2937 - 2941

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

2-Chloroinosine
2-Chlor-inosin
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