210880-92-5

210880-92-5 structure

Name: Clothianidin
Chemical Name: Clothianidin
CAS Number: 210880-92-5
Molecular Formula: C₆H₈ClN₅O₂S
Molecular Weight: 249.678
Catalog: Chemical pesticide Insecticide Organochlorine insecticide
Create Date: 2018-04-05 08:00:00
Modify Date: 2025-08-20 17:43:59
Clothianidin is a neonicotinoid insecticide. Clothianidin shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin has various application methods and high safety for crops[1].

Name	Clothianidin
Synonyms	TI 435 1-(2-Chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine Pancho 3-(2-chloro-5-thiazolylmethyl)-1-methyl-2-nitroguanidine (E)-1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine [C(E)]-N-[(2-Chloro-5-thiazolyl)methyl]-N′-methyl-N″-nitroguanidine Guanidine, N-[(2-chloro-5-thiazolyl)methyl]-N''-methyl-N'-nitro- Poncho 1-(2-chlorothiazol-5-ylmethyl)-2-nitro-3-methyl-guanidine Dantop MFCD06200753 1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine) (E)-1-(2-CHLORO-5-THIAZOLYLMETHYL)-3-METHYL-2-NITROGUANIDINE (E)-1-(2-Chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine (E)-1-(2-chlorothiazol-5-ylmethyl)-3-methyl-2-nitroguanidine 1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine Clothianidin Apacz T5N CSJ BG D1MYM1&UNNW &&E Form N-(2-chloro-5-thiazolylmethyl)-3-methyl-2-nitro-guanidine Celero Belay Clutch Dantotsu 1-[(2-chloro-5-thiazolyl)methyl]-3-methyl-2-nitroguanidine

Description	Clothianidin is a neonicotinoid insecticide. Clothianidin shows excellent long-term control effect in small doses against various insect pests such as Coleoptera, Thysanoptera, Lepidoptera, Diptera, Homoptera, Heteroptera, Orthoptera and Isoptera families. Clothianidin has various application methods and high safety for crops[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Clothianidin (30 nM) 在离体神经元上表现出高活性[2]。 Clothianidin (1 µg/L；36 h) 对马利筋中的帝王蝶幼虫显示出亚致死效应[3]。 Clothianidin (0.25 mg/粒和 0.50 mg/粒) 在玉米和大豆耕作的农田中，在土壤和水中浓度低[4]。
References	[1]. Uneme H. Chemistry of clothianidin and related compounds. J Agric Food Chem. 2011 Apr 13;59(7):2932-7. [2]. Nauen R, et al. Thiamethoxam is a neonicotinoid precursor converted to clothianidin in insects and plants[J]. Pesticide biochemistry and physiology, 2003, 76(2): 55-69. [3]. Pecenka JR, et al. Non-target effects of clothianidin on monarch butterflies. Naturwissenschaften. 2015 Apr;102(3-4):19. [4]. de Perre C, et al. Fate and effects of clothianidin in fields using conservation practices. Environ Toxicol Chem. 2015 Feb;34(2):258-65.

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H410
Precautionary Statements	P273-P301 + P312 + P330-P391-P501
Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn,Xi
Risk Phrases	R22:Harmful if swallowed. R36/37/38:Irritating to eyes, respiratory system and skin . R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Phrases	S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36:Wear suitable protective clothing . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S22:Do not breathe dust .
RIDADR	UN2811
WGK Germany	3
RTECS	ME9565000
Packaging Group	III
Hazard Class	6.1
HS Code	2934100016

187149-02-6

~98%

210880-92-5

Literature: Takeda Chemical Industries, Ltd. Patent: US6008363 A1, 1999 ;

57538-27-9

120740-08-1

~36%

210880-92-5

Literature: Takeda Chemical Industries, Ltd. Patent: US6008363 A1, 1999 ;

305838-80-6

210880-92-5

Literature: Tetrahedron Letters, , vol. 41, # 37 p. 7187 - 7191

Precursor 3
187149-02-6 57538-27-9 120740-08-1
DownStream 0

HS Code	2934100016
Summary	2934100016 (z)-1-((2-chlorothiazol-5-yl)methyl)-2-methyl-3-nitroguanidine。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%