77175-51-0
77175-51-0 structure
- Name: croconazole
- Chemical Name: croconazole
- CAS Number: 77175-51-0
- Molecular Formula: C18H15ClN2O
- Molecular Weight: 310.78
- Catalog: API Synthetic anti-infective drugs Antifungal drugs
- Create Date: 2018-08-11 11:34:53
- Modify Date: 2024-01-03 17:40:17
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Croconazole is an antifungal agent containing imidazole rings. Croconazole has a unique structural feature of aryl vinyl at the imidazole ring N-1. Croconazole can be used for the identification and quantitative study of major metabolites in rat urine and bile [1].
| Name | croconazole |
|---|---|
| Synonyms |
1-[1-[2-[(3-Chlorobenzyl)oxy]phenyl]ethenyl]-1H-imidazole
1-(1H-Imidazole-1-yl)-1-[2-(3-chlorobenzyloxy)phenyl]ethene Croconazole (Cloconazole) Cloconazole 1-[1-(2-(3-chlorobenzyloxy)phenyl)vinyl]imidazole 1-(1-{2-[(3-chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole Viniconazole Pilzcin |
| Description | Croconazole is an antifungal agent containing imidazole rings. Croconazole has a unique structural feature of aryl vinyl at the imidazole ring N-1. Croconazole can be used for the identification and quantitative study of major metabolites in rat urine and bile [1]. |
|---|---|
| Related Catalog | |
| References |
[1]. Nakano M, et al. Croconazole metabolism in rats.Xenobiotica. 1990 Apr;20(4):385-93. |
| Density | 1.16g/cm3 |
|---|---|
| Boiling Point | 501.5ºC at 760 mmHg |
| Melting Point | 72-73ºC |
| Molecular Formula | C18H15ClN2O |
| Molecular Weight | 310.78 |
| Flash Point | 257.1ºC |
| Exact Mass | 310.08700 |
| PSA | 27.05000 |
| LogP | 4.63450 |
| Index of Refraction | 1.593 |
| HS Code | 2933290090 |
|---|
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77175-51-0 |
| Literature: Ogata, Masaru; Matsumoto, Hiroshi; Shimizu, Sumio; Kida, Shiro; Shiro, Motoo; Tawara, Katsuya Journal of Medicinal Chemistry, 1987 , vol. 30, # 8 p. 1348 - 1354 |
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77175-51-0 |
| Literature: Ogata; Matsumoto; Hamada; Takehara; Tawara Journal of Medicinal Chemistry, 1983 , vol. 26, # 5 p. 768 - 770 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2933290090 |
|---|---|
| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |