73024-95-0

73024-95-0 structure

Name: Met-Enkephalin-Arg-Phe
Chemical Name: met-enkephalin-arg-phe
CAS Number: 73024-95-0
Molecular Formula: C₄₂H₅₆N₁₀O₉S
Molecular Weight: 877.02
Catalog: Research Areas Neurological Disease
Create Date: 2018-12-27 14:45:13
Modify Date: 2024-01-11 13:37:33
Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity[1].

Name	met-enkephalin-arg-phe
Synonyms	MERF TYR-GLY-GLY-PHE-MET-ARG-PHE METHIONINE ENKEPHALIN-ARG,PHE Tyr-Gly-Gly-Phe-Met-Arg-Phe-OH Met-Enkephalin-Arg-Phe MERF

Description	Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
In Vivo	Met-Enkephalin-Arg-Phe (10-100 nmol/mouse; i.c.v.; once) 在小鼠中有缓解疼痛活性[1]。 Animal Model: Male Swiss Webster mice[1] Dosage: 10-100 nmol/mouse Administration: Intracerebralventricular injection, once Result: Produced a dose-related inhibition of the tail-flick response. The effects peaked at 2-4 min and were dissipated by 10 min. The EC50 was 38.5 nmol/mouse.
References	[1]. Inturrisi CE, et al. Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7. Proc Natl Acad Sci U S A. 1980 Sep;77(9):5512-4.