Met-Enkephalin-Arg-Phe

Modify Date: 2024-01-11 13:37:33

Met-Enkephalin-Arg-Phe Structure
Met-Enkephalin-Arg-Phe structure
Common Name Met-Enkephalin-Arg-Phe
CAS Number 73024-95-0 Molecular Weight 877.02
Density 1.38g/cm3 Boiling Point N/A
Molecular Formula C42H56N10O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Met-Enkephalin-Arg-Phe


Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity[1].

 Names

Name met-enkephalin-arg-phe
Synonym More Synonyms

 Met-Enkephalin-Arg-Phe Biological Activity

Description Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity[1].
Related Catalog
In Vivo Met-Enkephalin-Arg-Phe (10-100 nmol/mouse; i.c.v.; once) 在小鼠中有缓解疼痛活性[1]。 Animal Model: Male Swiss Webster mice[1] Dosage: 10-100 nmol/mouse Administration: Intracerebralventricular injection, once Result: Produced a dose-related inhibition of the tail-flick response. The effects peaked at 2-4 min and were dissipated by 10 min. The EC50 was 38.5 nmol/mouse.
References

[1]. Inturrisi CE, et al. Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7. Proc Natl Acad Sci U S A. 1980 Sep;77(9):5512-4.  

 Chemical & Physical Properties

Density 1.38g/cm3
Molecular Formula C42H56N10O9S
Molecular Weight 877.02
Exact Mass 876.39500
PSA 345.35000
LogP 3.25660
Index of Refraction 1.65

 Synonyms

MERF
TYR-GLY-GLY-PHE-MET-ARG-PHE
METHIONINE ENKEPHALIN-ARG,PHE
Tyr-Gly-Gly-Phe-Met-Arg-Phe-OH
Met-Enkephalin-Arg-Phe MERF
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