Name | 3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid |
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Synonyms |
Saclofen
3-Amino-2-(4-chlorophenyl)propane-1-sulfonic acid UNII:LRZ36BCQ1Y Benzeneethanesulfonic acid, β-(aminomethyl)-4-chloro- MFCD00216817 3-Amino-2-(4-chlorophenyl)-1-propanesulfonic acid beta-(Aminomethyl)-4-chlorobenzeneethanesulfonic acid |
Description | Saclofen is a competitive antagonist of the GABAB receptor with an IC50 of 7.8 μM. Saclofen can be used to determine the functional roles for the GABAB receptor as a mediator of slow inhibitory postsynaptic potentials in the brain[1]. |
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Related Catalog | |
References |
Density | 1.437±0.06 g/cm3 |
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Melting Point | 310-315 ºC |
Molecular Formula | C9H12ClNO3S |
Molecular Weight | 249.714 |
Exact Mass | 249.022644 |
PSA | 88.77000 |
LogP | 0.03 |
Index of Refraction | 1.600 |
Storage condition | Store at RT |
Water Solubility | Slightly soluble (7.5 g/L) (25 ºC) |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
HS Code | 2921499090 |
~58% 125464-42-8 |
Literature: Li; Howson; Dolle Synthesis, 1991 , # 3 p. 244 - 244 |
~% 125464-42-8 |
Literature: Synthesis, , # 3 p. 244 - 244 |
~% 125464-42-8 |
Literature: Synthesis, , # 3 p. 244 - 244 |
Precursor 3 | |
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DownStream 0 |
HS Code | 2921499090 |
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Summary | 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |