- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: β-Amyloid-42
- Price:
- Purity: 95.0%
- Stocking Period: 10 Day
- Contact: Yang
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: Bate-Amyloid （ 1-42 ） human
- Price: $Inquiry/1kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: β-Amyloid-42
- Price: ￥Inquiry/1mg ￥2908.0/1mg ￥Inquiry/1mg
- Purity: 95.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- Nanjing Peptide Biotech Ltd
- China
- Product Name: β-Amyloid Peptide (1-42), rat
- Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
- Purity: 98.0%
- Stocking Period: 7 Day
- Contact: jom
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: beta-Amyloid (1-42) human
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
107761-42-2
107761-42-2 structure
- Name: β-Amyloid-42
- Chemical Name: Amyloid|A-Peptide (1-42) (human)
- CAS Number: 107761-42-2
- Molecular Formula: C203H311N55O60S
- Molecular Weight: 4514.04000
- Catalog: Biochemical Peptide
- Create Date: 2018-04-16 08:00:00
- Modify Date: 2024-01-01 23:11:10
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Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
| Name | Amyloid|A-Peptide (1-42) (human) |
|---|---|
| Synonyms |
β-amyloid 42
Amyloid Beta-Peptide (1-42) (human) beta-Amyloid (1-42) human β-amyloid polypeptide 42 β-amyloid protein 42 MFCD01864012 Human β-amyloid peptide (1-42) DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA Bate-Amyloid （ 1-42 ） human Amyloid β-Peptide (1-42) (human) |
| Description | Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. |
|---|---|
| Related Catalog | |
| In Vitro | Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. Application of Amyloid β-Peptide (1-42) human (1 to 10 μM) in the bathing solution does not change delayed rectifier K+-current and leakage current, but enhances inactivation of Са2+-current and blocks Са2+-dependent К+-current[1]. At 2.5 μM concentration, Amyloid β-Peptide (1-42) human reduces viability of SH-SY5Y cells to 65%. Results show that Amyloid β-Peptide (1-42) human localizes in both the cytoplasm and nucleus of SH-SY5Y cells after 30 min of incubation and after 8 h. In the latter, large accumulations of Amyloid β-Peptide (1-42) human are seen in the cytoplasm and in the nucleus. Increased APP mRNA levels are also detected upon Amyloid β-Peptide (1-42) human treatment[2]. |
| Cell Assay | SH-SY5Y cells are treated with biotinylated Amyloid β-Peptide (1-42) human peptide 1 μM. Cells are fixed and permeabilized with 3.3% formaldehyde containing 0.5% Triton X-100 followed by 125 mM glycine in PBS containing magnesium and calcium. Cells are blocked with 5% fetal bovine calf serum followed by the primary antibody. Biotin-Amyloid β-Peptide (1-42) human peptide is detected with the monoclonal antibody AB or alternatively with Avidin Fluor488. Nuclei are stained with DAPI. Images are obtained using an LSM 510 meta confocal microscope[2]. |
| Molecular Formula | C203H311N55O60S |
|---|---|
| Molecular Weight | 4514.04000 |
| Exact Mass | 4511.27000 |
| PSA | 1840.49000 |
| LogP | 1.35150 |
| Storage condition | −20°C |
| Safety Phrases | 24/25 |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29332900 |