107761-42-2
107761-42-2 structure
- Name: β-Amyloid-42
- Chemical Name: Amyloid|A-Peptide (1-42) (human)
- CAS Number: 107761-42-2
- Molecular Formula: C203H311N55O60S
- Molecular Weight: 4514.04000
- Catalog: Biochemical Peptide
- Create Date: 2018-04-16 08:00:00
- Modify Date: 2026-07-05 11:33:32
-
Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
| Name | Amyloid|A-Peptide (1-42) (human) |
|---|---|
| Synonyms |
REF DUPL: H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-g-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
β-amyloid 42 Amyloid|A-Ptide (human) Amyloidb-Ptide(human) Amyloid β-Protein Amyloid β-Protein (HFIP-treated) SS-AMYLOID PTIDE , RAT Amyloid &beta DA-42 β–Amyloid , human, Amyloid β-Protein (Human, ) BETA-AMYLOID PTIDE , HUMAN C203H311N55O60S H-asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-g-His-Gln-Lys-Leu-Val-Gly-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Ile-Ala-OH HuMan β-aMyloid ptide β-Amyloid: ,human beta-Amyloid humanbeta-Amyloid Beta-AMyloidTB beta-Amyloid human Β-AMYLOID PTIDE , RAT β-amyloid protein 42 Amyloid beta-Protein hydrochloride salt H-Asp-Ala-Glu-Phe-g-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH hydrochloride salt AMYLOID BETA-PTIDE (HUMAN) beta-Amyloid human //BP Amyloid β-Peptide (1-42) (human) Amyloid β Protein Fragment β-AMyloid Ptide ,rat,β-AMyloid Ptide ,rat Amyloid beta Protein fragment HCl Salt Amyloid β Protein Fragment ,human β-amyloid polypeptide 42 H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-g-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH H-Asp-Ala-Glu-Phe-g-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-OH Amyloid beta-Protein sodium salt Bate-Amyloid（）human Amyloid β-Protein hydrochloride salt beta-Amyloid (1-42) human β-Amyloid , human TFA Amyloid β-Ptide (human) TFA Bate-Amyloid （ 1-42 ） human Amyloid β-Ptide Amyloid-β Ptide soy ptide AMyloid b-Protein 2-Amyloid Human Amyloid β-Protein sodium salt (human) AB42, betaamyloid ptide L-alpha-Asptyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-ginyl-L-histidyl-L-alpha-asptyl-L-serylglycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-alpha-glutamyl-L-alpha-asptyl-L-valylglycyl-L-seryl-L-aspaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine beta-Amyloid human/TB500 Amyloid β Protein Fragment , (HPLC) DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA MFCD01864012 Human β-amyloid peptide (1-42) AMyloid huMan ptide Amyloid β-Ptide (human) Amyloid beta-Protein trifluoroacetate salt H-Asp-Ala-Glu-Phe-g-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH trifluoroacetate salt Asp-Ala-Glu-Phe-g-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala Soy Ptide Powder Soy Oligoptides Bate-Amyloid Amyloid Beta-Peptide (1-42) (human) AMYLOID B-PROTEIN FRAGMENT TB500 Human beta-amyloid ptide β–Amyloid , Amyloid β-Protein (Human, ) Beta-Amyloid , sodium salt |
| Description | Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. |
|---|---|
| Related Catalog | |
| In Vitro | Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease. Application of Amyloid β-Peptide (1-42) human (1 to 10 μM) in the bathing solution does not change delayed rectifier K+-current and leakage current, but enhances inactivation of Са2+-current and blocks Са2+-dependent К+-current[1]. At 2.5 μM concentration, Amyloid β-Peptide (1-42) human reduces viability of SH-SY5Y cells to 65%. Results show that Amyloid β-Peptide (1-42) human localizes in both the cytoplasm and nucleus of SH-SY5Y cells after 30 min of incubation and after 8 h. In the latter, large accumulations of Amyloid β-Peptide (1-42) human are seen in the cytoplasm and in the nucleus. Increased APP mRNA levels are also detected upon Amyloid β-Peptide (1-42) human treatment[2]. |
| Cell Assay | SH-SY5Y cells are treated with biotinylated Amyloid β-Peptide (1-42) human peptide 1 μM. Cells are fixed and permeabilized with 3.3% formaldehyde containing 0.5% Triton X-100 followed by 125 mM glycine in PBS containing magnesium and calcium. Cells are blocked with 5% fetal bovine calf serum followed by the primary antibody. Biotin-Amyloid β-Peptide (1-42) human peptide is detected with the monoclonal antibody AB or alternatively with Avidin Fluor488. Nuclei are stained with DAPI. Images are obtained using an LSM 510 meta confocal microscope[2]. |
| Molecular Formula | C203H311N55O60S |
|---|---|
| Molecular Weight | 4514.04000 |
| Exact Mass | 4511.27000 |
| PSA | 1840.49000 |
| LogP | 1.35150 |
| Storage condition | −20°C |
| Safety Phrases | 24/25 |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29332900 |