31428-61-2

31428-61-2 structure

Name: Tiamenidine
Chemical Name: N-(2-chloro-4-methylthiophen-3-yl)-4,5-dihydro-1H-imidazol-2-amine
CAS Number: 31428-61-2
Molecular Formula: C₈H₁₀ClN₃S
Molecular Weight: 215.70
Catalog: API Circulatory system medication Antihypertensive drug
Create Date: 2018-05-23 08:00:00
Modify Date: 2025-08-25 13:45:09
Tiamenidine (HOE 440) is an orally active α2-adrenergic receptor agonist with antihypertensive effect. Tiamenidine is used as an antihypertensive agent for hypertension research[1].

Name	N-(2-chloro-4-methylthiophen-3-yl)-4,5-dihydro-1H-imidazol-2-amine
Synonyms	Hoe-440 Tiamenidinum Hoe-42-440 Tiamenidine Tiamenidina

Description	Tiamenidine (HOE 440) is an orally active α2-adrenergic receptor agonist with antihypertensive effect. Tiamenidine is used as an antihypertensive agent for hypertension research[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	IC50: α2-Adrenergic Receptor[1]
References	[1]. D M Roden, et al. Electrophysiologic and hemodynamic effects of chronic oral therapy with the alpha 2-agonists clonidine and tiamenidine in hypertensive volunteers. Clin Pharmacol Ther. 1988 Jun;43(6):648-54.

HS Code	2934999090

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%