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4914-30-1

4914-30-1 structure
4914-30-1 structure
  • Name: Dehydroemetine
  • Chemical Name: (11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-4,6,7,11b-tetrahydro-1H-benzo[a]quinolizine
  • CAS Number: 4914-30-1
  • Molecular Formula: C29H38N2O4
  • Molecular Weight: 478.62300
  • Catalog: API Antiparasitic drug Anti-amebiasis and anti-trichomoniasis drugs
  • Create Date: 2018-04-03 08:00:00
  • Modify Date: 2024-01-09 14:28:14
  • Dehydroemetine, a synthetic analogue of emetine dihydrochloride, is used for visceral leishmaniasis. Dehydroemetine used for anti-parasites[1].

Name (11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-4,6,7,11b-tetrahydro-1H-benzo[a]quinolizine
Synonyms Dehydroemetinum
Dehidroemetina
2,3-didehydro-emetine
2,3-Didehydroemetin
Emetine,2,3-didehydro
10,11,6',7'-tetramethoxy-emet-2-ene
Mebadin
dehydroemetine
BT 436
2-Dehydroemetine
(-)-2,3-Dehydroemetine
Description Dehydroemetine, a synthetic analogue of emetine dihydrochloride, is used for visceral leishmaniasis. Dehydroemetine used for anti-parasites[1].
Related Catalog
References

[1]. Fouarge M, et al.Development of dehydroemetine nanoparticles for the treatment of visceral leishmaniasis.J Microencapsul. 1989 Jan-Mar;6(1):29-34.

Density 1.19g/cm3
Boiling Point 604.7ºC at 760mmHg
Melting Point 94-96°
Molecular Formula C29H38N2O4
Molecular Weight 478.62300
Flash Point 319.5ºC
Exact Mass 478.28300
PSA 52.19000
LogP 5.27430
Index of Refraction 1.606

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JY5095000
CHEMICAL NAME :
Emetine, 2,3-didehydro-
CAS REGISTRY NUMBER :
4914-30-1
LAST UPDATED :
199410
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C29-H38-N2-O4
MOLECULAR WEIGHT :
478.69

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
68800 ug/kg/24H (Continuous)
REFERENCE :
IMSCE2 IRCS Medical Science. (Lancaster, UK) V.12-14, 1984-86. For publisher information, see MSCREJ. Volume(issue)/page/year: 13,946,1985