68813-55-8
68813-55-8 structure
- Name: Oxantel (pamoate)
- Chemical Name: 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol
- CAS Number: 68813-55-8
- Molecular Formula: C36H32N2O7
- Molecular Weight: 604.65
- Catalog: analytical chemistry Standard Forensic and veterinary standards
- Create Date: 2018-07-24 17:11:56
- Modify Date: 2026-07-01 17:22:22
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Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms.
| Name | 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol |
|---|---|
| Synonyms |
4-[(3-cboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-cboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol
Einecs -6 Telopar Oxantel pamoate (USAN) Phenol pyrimidine cbendazim 4,4'-Methylenebis[3-hydroxy-2-naphthalenecboxylic Acid 3-[(1E)-2-(1,4,5,6-Tetrahydro-1-Methyl-2-pyriMidinyl)ethenyl]phenol HMS2093L04 Octahydronaphthol EINECS 272-332-6 4,4'-methylenebis[3-hydroxy-2-naphthoic] acid, compound with (E)-3-[2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl]phenol (1:1) OXANTEL PAMOATE Oxantel Pamoate, 10 mM in DMSO Pasite,inhibit,Inhibitor,Oxantel Pamoate,Oxantel Oxantel Ebonate (E)-3-(2-(1-Methyl-1,4,5,6-tetrahydropyrimidin-2-yl)vinyl)phenol 4,4'-methylenebis(3-hydroxy-2-naphthoate) (1:1) 2-Naphthalenecboxylic acid, 4,4-methylenebis3-hydroxy-, compd. with 3-(1E)-2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenylphenol (1:1) Oxantel embonate 4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with (E)-3-(2-(1,4,5,6-tetrahydro-1-methylpyrimidin-2-yl)vinyl)phenol (1:1) 1-methyl-2-(3-hydroxyphenylethenyl)-1,4,5,6-tetrahydropyrimidine compound with 4,4'-methylenebis(3-hydroxy-2-naphthoic acid) Telopar (TN) (E)-3-[2-(1,4,5,6-Tetrahydro-1-Methyl-2-pyriMidinyl)ethenyl]phenol 4,4'-Methylenebis[3-hydroxy-2-naphthalenecboxylate] Salt 1-METHYL-2-[3-HYDROXYPHENYLETHENYL]-1,4,5,6-TETRAHYDROPYRIMIDINE COMPOUND WITH 4,4'-METHYLENEBIS[3-HYDROXY-2-NAPHTHOIC ACID] UNII-UPY1D732T0 Phenol, 3-(2-(1,4,5,6-tetrahydro-1-methyl-2-pyrimidinyl)ethenyl), (E)-, 4,4'-methylenebis(3-hydroxy-2-naphthalenecboxylate) (1:1) (salt) |
| Description | Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms. |
|---|---|
| Related Catalog | |
| Target |
Antiparasitic[1] |
| In Vivo | The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus[1]. |
| References |
| Density | 1.09 g/cm3 |
|---|---|
| Boiling Point | 383.1ºC at 760 mmHg |
| Molecular Formula | C36H32N2O7 |
| Molecular Weight | 604.65 |
| Flash Point | 185.5ºC |
| PSA | 186.72000 |
| LogP | 7.41720 |
| Storage condition | -20℃ |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |