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  • DC Chemicals Limited
  • China
  • Product Name: Telopar
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


68813-55-8

68813-55-8 structure
68813-55-8 structure
  • Name: Oxantel (pamoate)
  • Chemical Name: 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol
  • CAS Number: 68813-55-8
  • Molecular Formula: C36H32N2O7
  • Molecular Weight: 604.65
  • Catalog: analytical chemistry Standard Forensic and veterinary standards
  • Create Date: 2018-07-24 17:11:56
  • Modify Date: 2024-01-02 14:50:01
  • Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms.

Name 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol
Synonyms Telopar (TN)
EINECS 272-332-6
UNII-UPY1D732T0
Telopar
HMS2093L04
Oxantel embonate
Oxantel pamoate (USAN)
OXANTEL PAMOATE
Oxantel (pamoate)
Description Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms.
Related Catalog
Target

Antiparasitic[1]

In Vivo The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus[1].
References

[1]. Keiser J, et al. Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. PLoS Negl Trop Dis. 2013;7(3):e2119.

Density 1.09 g/cm3
Boiling Point 383.1ºC at 760 mmHg
Molecular Formula C36H32N2O7
Molecular Weight 604.65
Flash Point 185.5ºC
PSA 186.72000
LogP 7.41720
Storage condition -20℃
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3