Oxantel (pamoate)
Modify Date: 2024-01-02 14:50:01
Oxantel (pamoate) structure
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Common Name | Oxantel (pamoate) | ||
|---|---|---|---|---|
| CAS Number | 68813-55-8 | Molecular Weight | 604.65 | |
| Density | 1.09 g/cm3 | Boiling Point | 383.1ºC at 760 mmHg | |
| Molecular Formula | C36H32N2O7 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 185.5ºC | |
Use of Oxantel (pamoate)Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms. |
| Name | 4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,3-[(E)-2-(1-methyl-5,6-dihydro-4H-pyrimidin-2-yl)ethenyl]phenol |
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| Synonym | More Synonyms |
| Description | Oxantel pamoate is a widely available dewormer, potently against Trichuris muris and Hookworms. |
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| Related Catalog | |
| Target |
Antiparasitic[1] |
| In Vivo | The activity of the veterinary drug Oxantel pamoate is studied against Trichuris muris, Ancylostoma ceylanicum and Necator americanus. An ED50s of 4.7 mg/kg is calculated for Oxantel pamoate against T. muris in mice. Combinations of Oxantel pamoate with pyrantel pamoate behaved antagonistically (combination index (CI)=2.53). Oxantel pamoate combined with Levamisole, Albendazole or Ivermectin using ratios based on their ED50s reveals antagonistic effects (CI=1.27, 1.90 and 1.27, respectively). A highly synergistic effect (CI=0.15) is observed when Oxantel pamoate-mebendazole is administered to T. muris-infected mice. Oxantel pamoate (10 mg/kg) lacks activity against Ancylostoma ceylanicum and Necator americanus[1]. |
| References |
| Density | 1.09 g/cm3 |
|---|---|
| Boiling Point | 383.1ºC at 760 mmHg |
| Molecular Formula | C36H32N2O7 |
| Molecular Weight | 604.65 |
| Flash Point | 185.5ºC |
| PSA | 186.72000 |
| LogP | 7.41720 |
| Storage condition | -20℃ |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Oxantel pamoate-albendazole for Trichuris trichiura infection.
N. Engl. J. Med. 370(7) , 610-20, (2014) Infections with soil-transmitted helminths (Ascaris lumbricoides, hookworm, and Trichuris trichiura) are widespread and often occur concomitantly. These parasitic-worm infections are typically treated... |
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Preventive anthelmintic chemotherapy--expanding the armamentarium.
N. Engl. J. Med. 370(7) , 665-6, (2014)
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Mechanisms underlying gut dysfunction in a murine model of chronic parasitic infection.
Am. J. Physiol. Gastrointest. Liver Physiol. 299 , G1354-G1360, (2010) Irritable bowel syndrome (IBS) is common in countries where chronic parasitic infestations are endemic. However, the relationship between parasitic infection and IBS is not clear. The aim of this stud... |
| Telopar (TN) |
| EINECS 272-332-6 |
| UNII-UPY1D732T0 |
| Telopar |
| HMS2093L04 |
| Oxantel embonate |
| Oxantel pamoate (USAN) |
| OXANTEL PAMOATE |
| Oxantel (pamoate) |
- DC Chemicals Limited
- China
- Product Name: Telopar
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Oxantel pamoate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Oxantel PaMoate
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
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Price: $79/10mM*1mLinDMSO
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