Top Suppliers:I want be here


86259-87-2

86259-87-2 structure
86259-87-2 structure
  • Name: Tetraethylene Glycol Monobenzyl Ether
  • Chemical Name: Tetraethylene Glycol Monobenzyl Ether
  • CAS Number: 86259-87-2
  • Molecular Formula: C15H24O5
  • Molecular Weight: 284.348
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-10-01 22:07:20
  • Modify Date: 2024-01-11 19:40:41
  • BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name Tetraethylene Glycol Monobenzyl Ether
Synonyms 1-Phenyl-2,5,8,11-tetraoxatridecan-13-ol
2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethanol
2,5,8,11-Tetraoxatridecan-13-ol, 1-phenyl-
Benzyl-PEG4-alcohol
BnO-PEG4-OH
Description BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Andrew P. Crew, et al. Tau-protein targeting protacs and associated methods of use. Patent. US20180125821A1.

Density 1.1±0.1 g/cm3
Boiling Point 398.7±32.0 °C at 760 mmHg
Molecular Formula C15H24O5
Molecular Weight 284.348
Flash Point 194.9±25.1 °C
Exact Mass 284.162384
PSA 57.15000
LogP 0.18
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.500
HS Code 2909499000

~94%

86259-87-2 structure

86259-87-2

Literature: WO2008/54466 A2, ; Page/Page column 32-33 ;

~85%

86259-87-2 structure

86259-87-2

Literature: Synthetic Communications, , vol. 20, # 6 p. 799 - 807

~89%

86259-87-2 structure

86259-87-2

Literature: WO2007/112100 A2, ; Page/Page column 44; 103; 110; 128; 130; 138 ;

~%

86259-87-2 structure

86259-87-2

Literature: Angewandte Chemie - International Edition, , vol. 48, # 7 p. 1248 - 1252

~38%

Detail
Literature: ACH - Models in Chemistry, , vol. 134, # 2-3 p. 241 - 252

~%

86259-87-2 structure

86259-87-2

Literature: ACH - Models in Chemistry, , vol. 134, # 2-3 p. 241 - 252

~%

86259-87-2 structure

86259-87-2

Literature: ACH - Models in Chemistry, , vol. 133, # 1-2 p. 21 - 26

~%

86259-87-2 structure

86259-87-2

Literature: ACH - Models in Chemistry, , vol. 134, # 2-3 p. 241 - 252

~%

Detail
Literature: Tetrahedron Letters, , vol. 38, # 4 p. 661 - 664
HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%