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135558-11-1

135558-11-1 structure
135558-11-1 structure
  • Name: Lobaplatin
  • Chemical Name: Platinum, [rel-(1R,2R)-1,2-cyclobutanedimethanamine-.kappa.N,.kappa.N'][(2S)-2-(hydroxy-.kappa.O)propanoato(2-)-.kappa.O]-, (SP-4-3)- (9CI) (CA INDEX NAME)
  • CAS Number: 135558-11-1
  • Molecular Formula: C9H16N2O3Pt
  • Molecular Weight: 395.31300
  • Catalog: Research Areas Cancer
  • Create Date: 2018-06-01 08:00:00
  • Modify Date: 2024-01-06 11:33:11
  • Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes. Lobaplatin (D-19466) shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2].

Name Platinum, [rel-(1R,2R)-1,2-cyclobutanedimethanamine-.kappa.N,.kappa.N'][(2S)-2-(hydroxy-.kappa.O)propanoato(2-)-.kappa.O]-, (SP-4-3)- (9CI) (CA INDEX NAME)
Description Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes. Lobaplatin (D-19466) shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2].
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References

[1]. Cao H, et al. Lobaplatin Inhibits Prostate Cancer Proliferation and Migration Through Regulation of BCL2 and BAX. Dose Response. 2019 Jun 5;17(2):1559325819850981.

[2]. McKeage MJ, et al. Lobaplatin: a new antitumour platinum drug. Expert Opin Investig Drugs. 2001 Jan;10(1):119-28.

Boiling Point 179.5ºC at 760 mmHg
Melting Point 220ºC
Molecular Formula C9H16N2O3Pt
Molecular Weight 395.31300
Flash Point 75.1ºC
Exact Mass 395.08100
PSA 75.27000
LogP 0.53800
Vapour Pressure 0.937mmHg at 25°C
Storage condition 2-8°C