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138-65-8

138-65-8 structure
138-65-8 structure
  • Name: Norepinephrine
  • Chemical Name: noradrenaline
  • CAS Number: 138-65-8
  • Molecular Formula: C8H11NO3
  • Molecular Weight: 169.178
  • Create Date: 2018-02-13 08:00:00
  • Modify Date: 2026-07-13 19:24:08
Name noradrenaline
Synonyms 1-(3,4-Dihydroxy)phenyl-2-aminoethanol
dl-Norinhrine(Norinhrine)
(+)-Norepinephrin
4-((R)-2-Amino-1-hydroxy-ethyl)-benzene-1,2-diol
(R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol
Norinhrine Impurity 15（Dopamine Impurity 7）
R-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol
DL-NORADRENALINE
DL-ARTERENOL
3,4-Dhydroxyphenylethanolamine
L-NORADRENALINE
4-dihydroxy-alpha-(aminomethyl)-(+-)-benzylalcoho
a-(Aminomethyl)-3,4-dihydroxybenzyl alcohol
(+/-)-Norepinephrine
(-)-a-(Aminomethyl)protocatechuyl alcohol
2-(3,4-Dihydroxyphenyl)-2-hydroxyethanamine
(-)-norepinephrine
(S)-2,3-dihydroxy-5-(1-hydroxy-2-(methylamino)ethyl)benzenesulfonic acid
Benzyl alcohol, alpha-(aminomethyl)-3,4-dihydroxy-, (.+/-.)
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (.+/-.)
2-Amino-1-(3,4-dihydroxyphenyl)ethanol
(R)-noradrenaline
(-)-(R)-Norepinephrine
DL-Noradrenaline
4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
DL-NORINHRINE
1,2-Benzenediol, 4-(2-amino-1-hydroxy)-, (dl)
Benzyl alcohol, a-(aminomethyl)-3,4-dihydroxy-, (+-)- (8CI)
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)
(-)-NORADRENALINE
4-[(1R)-2-amino-1-hydroxyéthyl]benzène-1,2-diol
L-NOREPINEPHRINE
1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)- (9CI)
Racemic norinhrine
EINECS 205-337-9
4-(1-Hydroxy-2-aminoethyl)catechol
Dopamine Impurity 32
DL-TERENOL
Norinhrine, racemic mixture
(±)-4-(2-amino-1-hydroxyethyl)pyrocatechol
norepinephrinum [INN_la]
4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol
(±)-Norinhrine(Norinhrine)
[3H]-(+/-)-Norepinephrine
(R)-(-)-norepinephrine
DL-NOREPINEPHRINE
Dopamine Impurity 7
4-[(1R)-2-Amino-1-hydroxyethyl]benzol-1,2-diol
Noradrenalin
[14C]-(+/-)-Norepinephrine
(R)-4-(2-amino-1-hydroxyethyl)benzene-1,2-diol
(R)-norepinephrine
Racemic norepinephrine
(-4-(2-amino-1-hydroxyethyl)pyrocatechol
4-[(1R)-2-Amino-1-hydroxyethyl]benzene-1,2-diol
MFCD00066505
(+)-Norinhrin
4-[(1RS)-2-amino-1-hydroxyethyl]-1,2-benzenediol
(±)-α-(Aminomethyl)-3,4-dihydroxybenzyl alcohol, DL-terenol, DL-Noradrenaline
Density 1.4±0.1 g/cm3
Boiling Point 442.6±40.0 °C at 760 mmHg
Melting Point -190ºC (dec.)
Molecular Formula C8H11NO3
Molecular Weight 169.178
Flash Point 221.5±27.3 °C
Exact Mass 169.073898
PSA 86.71000
LogP -0.88
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.659

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DN6300000
CHEMICAL NAME :
Benzyl alcohol, alpha-(aminomethyl)-3,4-dihydroxy-, (+-)-
CAS REGISTRY NUMBER :
138-65-8
LAST UPDATED :
199106
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C8-H11-N-O3
MOLECULAR WEIGHT :
169.20
WISWESSER LINE NOTATION :
Z1YQR CQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 68,501,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
130 ug/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 95,502,1949
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
15600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 68,501,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,64,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4700 ug/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Lungs, Thorax, or Respiration - other changes Kidney, Ureter, Bladder - inflammation, necrosis, or scarring of bladder
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 95,502,1949
Hazard Codes T+: Very toxic;
Risk Phrases R28
Safety Phrases S28;S45;S36/S37/S39
WGK Germany 3
RTECS DN6300000
HS Code 2922509090
HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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