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17013-01-3

17013-01-3 structure
17013-01-3 structure

Name Sodium fumarate
Synonyms 2-Butenedioic acid, sodium salt, (2E)- (1:2)
Disodium (2E)-but-2-enedioate
2-Butenedioic acid (E)-, sodium salt
FUMARIC ACID SODIUM SALT
sodium fumarate
UNII:0578QTK490
MFCD00064567
(E)-2-Butenedioic acid disodium salt
EINECS 241-087-7
Disodium (2E)-2-butenedioate
Fumaric acid disodium salt
Disodium Fumarate
Description Fumaric acid (disodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog
Target

Human Endogenous Metabolite

Boiling Point 355.5ºC at 760 mmHg
Molecular Formula C4H2Na2O4
Molecular Weight 160.036
Flash Point 183ºC
Exact Mass 159.974854
PSA 80.26000
Vapour Pressure 5.19E-06mmHg at 25°C
Water Solubility 228 g/L

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LT1830000
CHEMICAL NAME :
Fumaric acid, disodium salt
CAS REGISTRY NUMBER :
17013-01-3
LAST UPDATED :
199107
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H2-O4.2Na
MOLECULAR WEIGHT :
160.04
WISWESSER LINE NOTATION :
QV1U1VQ &-NA- 2 -T

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
215 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting Gastrointestinal - other changes
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 31,1,1942
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,314,1986
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2420 mg/kg
TOXIC EFFECTS :
Behavioral - irritability Blood - hemorrhage Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 35,298,1946
TYPE OF TEST :
LD10 - Lethal Dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3680 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 31,12,1942
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 31,1,1942
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS LT1830000
HS Code 2917190090

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17013-01-3 structure

17013-01-3

Literature: WO2006/26026 A2, ; Page/Page column 69 ;

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17013-01-3 structure

17013-01-3

Literature: Bulletin of the Chemical Society of Japan, , vol. 65, # 4 p. 1168 - 1169

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17013-01-3 structure

17013-01-3

Literature: Journal of the Indian Chemical Society, , vol. 67, # 5 p. 381 - 383
HS Code 2917190090
Summary 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%