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488-59-5

488-59-5 structure
488-59-5 structure
  • Name: scyllo-Inositol
  • Chemical Name: scyllo-inositol
  • CAS Number: 488-59-5
  • Molecular Formula: C6H12O6
  • Molecular Weight: 180.156
  • Catalog: Biochemical Carbohydrate Monosaccharide
  • Create Date: 2018-06-11 00:16:22
  • Modify Date: 2024-01-02 16:31:59
  • Scyllo-Inositol, an amyloid inhibitor, potentialy inhibits α-synuclein aggregation. Scyllo-Inositol stabilizes a non-fibrillar non-toxic form of amyloid-β peptide (Aβ42) in vitro, reverses cognitive deficits, and reduces synaptic toxicity and loweres amyloid plaques in an Alzheimer's disease mouse model[1].

Name scyllo-inositol
Synonyms ELND 005
MFCD00065455
Cocositol
AZD 103
1,3,5 2,4,6-Hexahydroxycyclohexane
SCYLLITO
scyllo-Cyclohexanehexol
(1a,2b,3a,4b,5a,6b)-Cyclohexanehexol
cyclohexane-1r,2t,3c,4t,5c,6t-hexaol
1,3,5 2,4,6-Hexahydroxycyclohexane DTLET
1,2,3,4,5,6-Cyclohexanehexol, (1α,2β,3α,4β,5α,6β)-
Scyllitol
Inositol,scyllo
1,3,5/2,4,6-HEXAHYDROXYCYCLOHEXANE
Quercinitol
(1r,2r,3r,4r,5r,6r)-1,2,3,4,5,6-Cyclohexanehexol
(1r,2r,3r,4r,5r,6r)-Cyclohexane-1,2,3,4,5,6-hexol
1,3,5/2,4,6-Inositol
scyllo-Inositol
scyllo-inosotol
Description Scyllo-Inositol, an amyloid inhibitor, potentialy inhibits α-synuclein aggregation. Scyllo-Inositol stabilizes a non-fibrillar non-toxic form of amyloid-β peptide (Aβ42) in vitro, reverses cognitive deficits, and reduces synaptic toxicity and loweres amyloid plaques in an Alzheimer's disease mouse model[1].
Related Catalog
References

[1]. Ibrahim T, et al. α-Synuclein aggregation, seeding and inhibition by scyllo-inositol. Biochem Biophys Res Commun. 2016 Jan 15;469(3):529-34.

Density 2.0±0.1 g/cm3
Boiling Point 291.3±40.0 °C at 760 mmHg
Melting Point 350ºC
Molecular Formula C6H12O6
Molecular Weight 180.156
Flash Point 143.4±21.9 °C
Exact Mass 180.063385
PSA 121.38000
LogP -2.11
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.784
Storage condition -20°C Freezer
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2906199090
HS Code 2906199090
Summary 2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%