68766-96-1
68766-96-1 structure
- Name: H-D-Pyr-OEt
- Chemical Name: Ethyl D-(-)-pyroglutamate
- CAS Number: 68766-96-1
- Molecular Formula: C7H11NO3
- Molecular Weight: 157.167
- Catalog: Biochemical Amino acids and their derivatives Glutamic acid derivative
- Create Date: 2018-02-12 08:00:00
- Modify Date: 2026-07-02 09:14:25
| Name | Ethyl D-(-)-pyroglutamate |
|---|---|
| Synonyms |
(R)-5-Oxo-2-pyrrolidinecboxylic acid ethyl ester
Ethyl (R)-(-)-2-pyrrolidone-5-cboxylate（H-D-Pyr-Oet） ETHYL (R)-2-PYRROLIDINONE-5-CBOXYLATE (R)-(-)-ETHYL-2-PYRROLLIDONE-5-CBOXYLATE D-Pyroglutamic ethyl ester (R)-5-OXOPROLINE ETHYL ESTER Ethyl D-(-)-pyroglutamate //BP Ethyl (R)-(-)-2-pyrrolidone-5-cboxylate Ethyl D-2-Pyrrolidinone-5-cboxylate ethyl (2R)-5-oxopyrrolidine-2-cboxylate (R)-5-Oxopyrrolidine-2-cboxylic Acid Ethyl Ester Ethyl 5-oxo-D-prolinate D-PYROGLUTAMIC ACID ETHYL ESTER (R)-ETHYLPYROGLUTAMATE (R)-5-Oxoproline ethyl ester, D-5-Oxo-2-pyrrolidinecboxylic acid ethyl ester D-Proline, 5-oxo-, ethyl ester (R)-(-)-2-PYRROLIDINONE-5-CBOXYLATE ETHYL ESTER H-D-PGLU-OET ETHYL 5-OXO-D-PROLINE (R)-(-)-5-Ethylcboxyl-2-pyrrolidinone Ethyl (R)-(-)-2-pyrrolidone-5-cboxylateD(-)-Pyroglutamic acid ethyl esterEthyl (R)-(-)-pyroglutamateEthyl D(-)-pyroglutamate H-D-PYR-OET Ethyl D-2-Pyrrolidinone-5-cboxylate,e.e 5-Oxo-D-proline Ethyl Ester (-)-D-PYROGLUTAMIC ACID ETHYL ESTER ETHYL PYROGLUTAMATE ethyl (2R)-5-oxopyrrolidine-2-carboxylate Ethyl (R)-()-2-pyrrolidone-5-cboxylate MFCD00010848 D-5-OXO-2-PYRROLIDINECBOXYLIC ACID ETHYL ESTER (R)-5-Oxoproline ethyl ester, D-5-Oxo-2-pyrrolidinecboxylic acid ethyl ester, D-Pyroglutamic acid ethyl ester, Ethyl 5-oxo-D-proline, Ethyl pyroglutamate D-PYR-OET (2R)-5-Oxo-2β-pyrrolidinecboxylic acid ethyl ester D-Pyroglutamic acid ethyl ester (NMR) D-Pyroglutamate ethyl ester |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 312.7±35.0 °C at 760 mmHg |
| Melting Point | 49-53ºC |
| Molecular Formula | C7H11NO3 |
| Molecular Weight | 157.167 |
| Flash Point | 142.9±25.9 °C |
| Exact Mass | 157.073898 |
| PSA | 55.40000 |
| LogP | -1.39 |
| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
| Index of Refraction | 1.466 |
| Storage condition | 2~8°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
|
~99%
68766-96-1 |
| Literature: Ibrahim, Mohamed A.; Johnson, Henry W. B.; Jeong, Joon Won; Lewis, Gary L.; Shi, Xian; Noguchi, Robin T.; Williams, Matthew; Leahy, James W.; Nuss, John M.; Woolfrey, John; Banica, Monica; Bentzien, Frauke; Chou, Yu-Chien; Gibson, Anna; Heald, Nathan; Lamb, Peter; Mattheakis, Larry; Matthews, David; Shipway, Aaron; Wu, Xiang; Zhang, Wentao; Zhou, Sihong; Shankar, Geetha Journal of Medicinal Chemistry, 2012 , vol. 55, # 3 p. 1368 - 1381 |
|
~87%
68766-96-1 |
| Literature: Evans; Lundy Journal of the American Chemical Society, 1992 , vol. 114, # 4 p. 1495 - 1496 |
|
~%
68766-96-1 |
| Literature: Hamada; Hara; Kawai; Kohno; Shioiri Tetrahedron, 1991 , vol. 47, # 40 p. 8635 - 8652 |
|
~%
68766-96-1 |
| Literature: Tetrahedron, , vol. 47, # 40 p. 8635 - 8652 |
|
~%
68766-96-1 |
|
Literature: Sexagint, Festschrift |
| Precursor 5 | |
|---|---|
| DownStream 6 | |
![(3S,7aR)-3-Phenyltetrahydro-5H-pyrrolo[1,2-c][1,3]oxazol-5-one structure](https://image.chemsrc.com/caspic/297/118918-76-6.png)
![(3S,7aR)-3-Phenyl-1,7a-dihydro-5H-pyrrolo[1,2-c][1,3]oxazol-5-one structure](https://image.chemsrc.com/caspic/384/118867-99-5.png)