221093-38-5

221093-38-5 structure

Name: 4-Hydroxy-17β-estradiol-1,2,16,16,17-d5
Chemical Name: (8R,9S,13S,14S,17S)-16,16,17-trideuterio-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthrene-3,4,17-triol
CAS Number: 221093-38-5
Molecular Formula: C₁₈H₁₉D₅O₃
Molecular Weight: 293.41
Catalog: Signaling Pathways Others Others
Create Date: 2018-05-16 08:00:00
Modify Date: 2024-02-01 13:15:04
4-Hydroxy-17β-estradiol-1,2,16,16,17-d5 is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17[1].

Name	(8R,9S,13S,14S,17S)-16,16,17-trideuterio-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthrene-3,4,17-triol
Synonyms	4-Hydroxyestradiol-16,16,17-d5 4-Hydroxy-17\|A-estradiol-16,16,17-d5

Description	4-Hydroxy-17β-estradiol-1,2,16,16,17-d5 is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17[1].
Related Catalog	Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.