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23291-96-5

23291-96-5 structure
23291-96-5 structure
  • Name: Dehydromonocrotaline
  • Chemical Name: Dehydromonocrotaline
  • CAS Number: 23291-96-5
  • Molecular Formula: C16H21NO6
  • Molecular Weight: 323.34100
  • Create Date: 2017-12-03 06:47:41
  • Modify Date: 2024-01-05 16:21:53

Name Dehydromonocrotaline
Synonyms |A,|A-Dehydrolovastatin
Dehydro Lovastatin
Dehydromonacolin K
monocrotaline pyrrole
Density 1.43g/cm3
Boiling Point 557ºC at 760mmHg
Molecular Formula C16H21NO6
Molecular Weight 323.34100
Flash Point 290.6ºC
Exact Mass 323.13700
PSA 97.99000
LogP 0.67100
Vapour Pressure 3.06E-13mmHg at 25°C
Index of Refraction 1.62

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RC1250000
CHEMICAL NAME :
20-Norcrotalanan-11,15-dione, 3,8-didehydro-14,19-dihydro-12,13-dihydroxy-, (13-alpha,14- alpha)-
CAS REGISTRY NUMBER :
23291-96-5
LAST UPDATED :
199606
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C16-H21-N-O6
MOLECULAR WEIGHT :
323.38
WISWESSER LINE NOTATION :
T55-11- 1A P EN IOV NVO BU FUTJ K1 LQ L1 MQ M1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
16 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Liver - other changes
REFERENCE :
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 12,299,1976
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPTLAS Journal of Pathology. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.97- 1969- Volume(issue)/page/year: 100,169,1970 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3 mg/kg/5W-I
TOXIC EFFECTS :
Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
JPTLAS Journal of Pathology. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.97- 1969- Volume(issue)/page/year: 118,121,1976 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1504 mg/kg/47W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 17,61,1982
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