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38398-32-2

38398-32-2 structure
38398-32-2 structure
  • Name: Ganaxolone
  • Chemical Name: 1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone
  • CAS Number: 38398-32-2
  • Molecular Formula: C22H36O2
  • Molecular Weight: 332.52000
  • Create Date: 2017-09-04 22:03:57
  • Modify Date: 2025-08-25 10:51:35
  • Ganaxolone, also known as CCD 1042 and C1042, is a CNS-selective GABAA modulator that acts on well-characterized targets in the brain known to have anxiolytic and anticonvulsant effects. Ganaxolone protects against seizures in diverse animal models, including the pentylenetetrazol, 6 Hz and amygdala kindling models. Ganaxolone is a positive allosteric modulator of the action of the GABAA receptor and, unlike benzodiazepines, there does not appear to be tolerance to the anticonvulsant effects of ganaxolone.

Name 1-[(3R,5S,8R,9S,10S,13S,14S,17S)-3-hydroxy-3,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone
Synonyms ccd-1042
Ganaxolone
Density 1.036g/cm3
Boiling Point 434.8ºC at 760mmHg
Molecular Formula C22H36O2
Molecular Weight 332.52000
Flash Point 185.4ºC
Exact Mass 332.27200
PSA 37.30000
LogP 4.98530
Index of Refraction 1.517
Safety Phrases 22-24/25
RIDADR NONH for all modes of transport
RTECS TU4384700
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