145775-14-0

145775-14-0 structure

Name: NEP-IN-2
Chemical Name: N-[2-(2-Methylbenzyl)-3-sulfanylpropanoyl]-L-methionine
CAS Number: 145775-14-0
Molecular Formula: C₁₆H₂₃NO₃S₂
Molecular Weight: 341.48900
Catalog: Signaling Pathways Metabolic Enzyme/Protease Neprilysin
Create Date: 2017-01-28 18:26:40
Modify Date: 2026-07-27 18:39:58
NEP-IN-2 is an inhibitor of neutral endopeptidase, used in the research of proliferation in atherosclerosis, restenosis.

Name	N-[2-(2-Methylbenzyl)-3-sulfanylpropanoyl]-L-methionine
Synonyms	(R,R)-formoterol fumarate N-[2-mercaptomethyl-3-(2-methylphenyl)propionyl]-methionine N-[2-mercaptomethyl-3-(2-methylphenyl)propioyl]-methionine N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-(4-methoxyphenyl)-1-methylethyl]-amino]ethyl]phenyl]formamide (2S)-2-(3-mercapto-2-(2-methylbenzyl)propanamido)-4-(methylthio)butanoic acid Eformoterol fumarate FORMATEROL FUMATATE NIN 2,NIN2 2-[[2-[(2-Methylphenyl)methyl]-3-sulfanylpropanoyl]amino]-4-methylsulfanylbutanoic acid L-Methionine, N-[2-(mercaptomethyl)-3-(2-methylphenyl)-1-oxopropyl] FarMeterol N-(2(S)-(Mercaptomethyl)-3-(2-Methylphenyl)-1- Oxopropyl)-L-Methionine ForMaterol FuMarate Aformoterol N-IN-2

Description	NEP-IN-2 is an inhibitor of neutral endopeptidase, used in the research of proliferation in atherosclerosis, restenosis.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Neprilysin Research Areas >> Cardiovascular Disease
Target	Neutral endopeptidase[1]
In Vitro	NEP-IN-2 is an inhibitor of neutral endopeptidase (NEP), used in the research of proliferation in atherosclerosis, restenosis induced by angioplasty or vascular reconstructive surgery, glomerulonephritis, glomerulosclerosis or other diseases involving vascular cell proliferation[1].
References	[1]. Davis, Harry R., et al. Pharmaceutical compositions comprising natriuretic peptides or neutral endopeptidase inhibitors for treating and preventing myointimal proliferation. EP0533084 Kind Code: A1