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65273-66-7

65273-66-7 structure
65273-66-7 structure
  • Name: N-Dipropyldopamine hydrobromide
  • Chemical Name: 4-[2-(dipropylamino)ethyl]benzene-1,2-diol,hydrobromide
  • CAS Number: 65273-66-7
  • Molecular Formula: C14H24BrNO2
  • Molecular Weight: 318.25
  • Catalog: Research Areas Cancer
  • Create Date: 2018-07-19 23:06:43
  • Modify Date: 2024-01-06 08:13:04
  • N. N-dipropyrldopamine is a potent inhibitor of glutamate release and has anticancer activity. The increase of glutamate secretion leads to cancer-induced bone pain (CIBP). N. N-dipropyrldopamine plays an analgesic role in CIBP[1].

Name 4-[2-(dipropylamino)ethyl]benzene-1,2-diol,hydrobromide
Synonyms 3,4-dihydroxy-N,N-di-(n-propyl)phenethylamine hydrobromide
N,N-Dipropyldopamine
N,N-di-n-propyldopamine hydrobromide
N,N-Dipropyldopamine hydrobromide
Dipropyldopamine hydrobromide
N,N-di-n-propyldopamine
Description N. N-dipropyrldopamine is a potent inhibitor of glutamate release and has anticancer activity. The increase of glutamate secretion leads to cancer-induced bone pain (CIBP). N. N-dipropyrldopamine plays an analgesic role in CIBP[1].
Related Catalog
Target

cystine/glutamate transporter (XC-)[1]IC50:25.45 μM (cystine/glutamate transporter, XC-)[1]

References

[1]. Fazzari J, et al. Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain. Sci Rep. 2015 Feb 11;5:8380.  

Molecular Formula C14H24BrNO2
Molecular Weight 318.25
Exact Mass 317.09900
PSA 43.70000
LogP 3.72040
WGK Germany 3
RTECS RB5962000
HS Code 2922299090

~89%

65273-66-7 structure

65273-66-7

Literature: Casagrande; Santangelo; Saini; Doggi; Gerli; Cerri Arzneimittel-Forschung/Drug Research, 1986 , vol. 36, # 2 A p. 291 - 303
Precursor  1

DownStream  0

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%