756525-90-3

756525-90-3 structure

Name: m-PEG8-NHS ester
Chemical Name: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CAS Number: 756525-90-3
Molecular Formula: C₂₂H₃₉NO₁₂
Molecular Weight: 509.54500
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2017-05-22 12:42:30
Modify Date: 2024-01-11 18:30:30
m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Name	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Synonyms	AmbotzPEG1885 4,7,10,13,16,19,22,25-Octaoxahexacosanoic Acid N-Succinimidyl Ester N-Succinimidyl 4,7,10,13,16,19,22,25-Octaoxahexacosanoate M2187 MeO-dPEG(8)-NHS Methyl-PEG8-NHS Ester

Description	m-PEG8-NHS ester is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Inflammation/Immunology
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. By Boehnke, et al. Preparation of antibody drug conjugates with NAMPT inhibitors for use in treatment of cancer. Patent WO2019149637A1.