21363-18-8

21363-18-8 structure

21363-18-8 structure

Name: Viminol
Chemical Name: 1-[1-[(2-chlorophenyl)methyl]pyrrol-2-yl]-2-[di(butan-2-yl)amino]ethanol
CAS Number: 21363-18-8
Molecular Formula: C₂₁H₃₁ClN₂O
Molecular Weight: 362.94
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2018-06-19 11:06:05
Modify Date: 2024-01-02 11:20:46
Viminol is a centrally acting analgesic agent. Viminol also shows antitussive activity[1][2].

Name	1-[1-[(2-chlorophenyl)methyl]pyrrol-2-yl]-2-[di(butan-2-yl)amino]ethanol
Synonyms	1-[1-(2-chloro-benzyl)-pyrrol-2-yl]-2-(di-sec-butyl-amino)-ethanol Viminol Viminol [INN] Viminolo [DCIT] Diviminol EINECS 244-347-8 Viminolo [Italian] Viminolum [INN-Latin]

Description	Viminol is a centrally acting analgesic agent. Viminol also shows antitussive activity[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
References	[1]. D Chiarino, et al. Stereochemistry of viminol, a novel central analgesic. Arzneimittelforschung. 1978;28(9):1554-61. [2]. G Sabot, et al. Controlled evaluation of the antitussive activity of viminol p-hydroxybenzoate. Int J Clin Pharmacol Biopharm. 1977 Apr;15(4):181-3.

Density	1.07g/cm3
Boiling Point	321.3ºC at 760mmHg
Molecular Formula	C₂₁H₃₁ClN₂O
Molecular Weight	362.94
Flash Point	148.1ºC
Exact Mass	362.21200
PSA	28.40000
LogP	5.12220
Vapour Pressure	0.000125mmHg at 25°C
Index of Refraction	1.544

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UX9635500

CHEMICAL NAME :: Pyrrole-2-methanol, 1-(o-chlorobenzyl)-alpha-((di-sec-butylamino)methyl)-

CAS REGISTRY NUMBER :: 21363-18-8

BEILSTEIN REFERENCE NO. :: 0444219

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H31-Cl-N2-O

MOLECULAR WEIGHT :: 362.99

WISWESSER LINE NOTATION :: T5NJ A1R BG& BYQ1NY2&1&Y2&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 325 mg/kg

TOXIC EFFECTS :: Behavioral - analgesia

REFERENCE :: BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,5,1972