348079-17-4

348079-17-4 structure

Name: Ac-Ile-Glu-Thr-Asp-AMC
Chemical Name: N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-methyl-2-oxo-2H -chromen-7-yl)-L-α-asparagine
CAS Number: 348079-17-4
Molecular Formula: C₃₁H₄₁N₅O₁₂
Molecular Weight: 675.683
Catalog: Research Areas Others
Create Date: 2016-06-17 22:10:53
Modify Date: 2025-08-21 15:45:22
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity[1].

Name	N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-methyl-2-oxo-2H -chromen-7-yl)-L-α-asparagine
Synonyms	L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- N-Acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-α-asparagine

Description	Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. V Frost, et al. Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27(KIP1) in transformed lymphoid cells. Oncogene. 2001 May 17;20(22):2737-48.