Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 6-NITRO-2-[(6-NITRO-1H-BENZIMIDAZOL-2-YL)METHOXYMETHYL]-1H-BENZIMIDAZOLE HYDROCHLORIDE
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: VU591
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: VU591
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-nitro-2-{[(6-nitro-1H-benzimidazol-2-yl)methoxy]methyl}-1H-benzimidazole
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

1222810-74-3

1222810-74-3 structure

1222810-74-3 structure

Name: VU591
Chemical Name: 6-nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole
CAS Number: 1222810-74-3
Molecular Formula: C₁₆H₁₂N₆O₅
Molecular Weight: 368.30
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2016-06-10 12:38:04
Modify Date: 2025-08-23 10:22:32
VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM[1].

Name	6-nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole
Synonyms	2,2 inverted exclamation marka-(oxydimethanediyl)bis(5-nitro-1H-benzimidazole) ML112 2,2 inverted exclamation marka-(oxydimethanediyl)bis(6-nitro-1H-benzimidazole) 5-nitro-2-{[(6-nitro-1H-benzimidazol-2-yl)methoxy]methyl}-1H-benzimidazole VU591

Description	VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	IC50: 0.24 μM (ROMK)[1].
References	[1]. Bhave G, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011 Jan;79(1):42-50.

Molecular Formula	C₁₆H₁₂N₆O₅
Molecular Weight	368.30
Exact Mass	368.08700
PSA	158.23000
LogP	4.01880

RIDADR	NONH for all modes of transport

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