139953-20-1

139953-20-1 structure

Name: triptonoditerpenic acid
Chemical Name: 8-hydroxy-6-methoxy-1,4a-dimethyl-7-propan-2-yl-4,9,10,10a-tetrahydro-3H-phenanthrene-2-carboxylic acid
CAS Number: 139953-20-1
Molecular Formula: C₂₁H₂₈O₄
Molecular Weight: 344.44500
Catalog: Research Areas Cancer
Create Date: 2017-03-27 06:34:50
Modify Date: 2024-01-30 11:58:29

Name	8-hydroxy-6-methoxy-1,4a-dimethyl-7-propan-2-yl-4,9,10,10a-tetrahydro-3H-phenanthrene-2-carboxylic acid
Synonyms	2-Phenanthrenecarboxylic acid,3,4,4a,9,10,10a-hexahydro-8-hydroxy-6-methoxy-1,4a-dimethyl-7-(1-methylethyl) Triptonoditerpenic acid

Description
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 42.53 μM (HepG2), 29.74 μM (Hep3B), 37.63 μM (Bcap37)[1].
In Vitro	Triptonoditerpenic acid 对 HepG2、Hep3B 和 Bcap37 具有细胞毒性，IC50 值分别为 42.53 μM、29.74 μM 和 37.63 μM[1]。
References	[1]. Chang Gao, et al. Kaurane and abietane diterpenoids from the roots of Tripterygium wilfordii and their cytotoxic evaluation. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2942-2946.