1453-97-0
1453-97-0 structure
- Name: 5-benzyloxygramine
- Chemical Name: N,N-dimethyl-1-(5-phenylmethoxy-1H-indol-3-yl)methanamine
- CAS Number: 1453-97-0
- Molecular Formula: C18H20N2O
- Molecular Weight: 280.36400
- Catalog: Research Areas Others
- Create Date: 2018-03-11 08:00:00
- Modify Date: 2024-01-20 19:31:39
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5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1].
| Name | N,N-dimethyl-1-(5-phenylmethoxy-1H-indol-3-yl)methanamine |
|---|---|
| Synonyms |
5-benzyloxy-N,N-dimethylamino-3-methylindole
EINECS 215-927-8 5-Benzyloxy-gramin 5-Benzyloxygramine MFCD00005631 |
| Description | 5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic interactions with both partners, resulting in abnormal N protein oligomerization that was further confirmed in the cell[1]. |
| References |
| Density | 1.153g/cm3 |
|---|---|
| Boiling Point | 442.3ºC at 760mmHg |
| Melting Point | 137-139 °C(lit.) |
| Molecular Formula | C18H20N2O |
| Molecular Weight | 280.36400 |
| Flash Point | 221.3ºC |
| Exact Mass | 280.15800 |
| PSA | 28.26000 |
| LogP | 3.80850 |
| Vapour Pressure | 5.06E-08mmHg at 25°C |
| Storage condition | 2-8°C |
| Hazard Codes | C: Corrosive;Xi: Irritant; |
|---|---|
| Risk Phrases | R34 |
| Safety Phrases | S45-S36/37/39-S26 |
| HS Code | 2933990090 |
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~94%
1453-97-0 |
| Literature: Bandini, Marco; Eichholzer, Astrid Angewandte Chemie - International Edition, 2009 , vol. 48, # 50 p. 9533 - 9537 |
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| Literature: Journal of the American Chemical Society, , vol. 76, p. 5579,5584 |
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| Literature: Helvetica Chimica Acta, , vol. 38, p. 1452,1469 |
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| Literature: Helvetica Chimica Acta, , vol. 38, p. 1452,1469 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |