1453-97-0
1453-97-0 structure
- Name: 5-benzyloxygramine
- Chemical Name: N,N-dimethyl-1-(5-phenylmethoxy-1H-indol-3-yl)methanamine
- CAS Number: 1453-97-0
- Molecular Formula: C18H20N2O
- Molecular Weight: 280.36400
- Catalog: Research Areas Others
- Create Date: 2018-03-11 08:00:00
- Modify Date: 2026-08-23 21:28:13
-
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1].
| Name | N,N-dimethyl-1-(5-phenylmethoxy-1H-indol-3-yl)methanamine |
|---|---|
| Synonyms |
5-Benzyloxyamine
5-BENZYLOXY-3-(DIMETHYLAMINOMETHYL)INDOLE EINECS 215-927-8 5-Benzyloxy-gramin Inhibitor,inhibit,5Benzyloxyamine,5-Benzyloxyamine,5 Benzyloxyamine 5-Benzyloxygramine 5-benzyloxy-N,N-dimethylamino-3-methylindole 5-BENZYLOXYAMINE CRYSTALLINE 3-(Dimethylaminomethyl)-5-(benzyloxy)-1H-indole 1H-Indole-3-methanamine, N,N-dimethyl-5-(phenylmethoxy) N-[[5-(BENZYLOXY)-1H-INDOL-3-YL]METHYL]-N,N-DIMETHYLAMINE TIMTEC-BB SBB003021 5-Benzyloxy-3-(dimethylaminomethyl)-1H-indole MFCD00005631 |
| Description | 5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. |
|---|---|
| Related Catalog | |
| In Vitro | 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic interactions with both partners, resulting in abnormal N protein oligomerization that was further confirmed in the cell[1]. |
| References |
| Density | 1.153g/cm3 |
|---|---|
| Boiling Point | 442.3ºC at 760mmHg |
| Melting Point | 137-139 °C(lit.) |
| Molecular Formula | C18H20N2O |
| Molecular Weight | 280.36400 |
| Flash Point | 221.3ºC |
| Exact Mass | 280.15800 |
| PSA | 28.26000 |
| LogP | 3.80850 |
| Vapour Pressure | 5.06E-08mmHg at 25°C |
| Storage condition | 2-8°C |
| Hazard Codes | C: Corrosive;Xi: Irritant; |
|---|---|
| Risk Phrases | R34 |
| Safety Phrases | S45-S36/37/39-S26 |
| HS Code | 2933990090 |
|
~94%
1453-97-0 |
| Literature: Bandini, Marco; Eichholzer, Astrid Angewandte Chemie - International Edition, 2009 , vol. 48, # 50 p. 9533 - 9537 |
|
~%
1453-97-0 |
| Literature: Journal of the American Chemical Society, , vol. 76, p. 5579,5584 |
|
~%
1453-97-0 |
| Literature: Helvetica Chimica Acta, , vol. 38, p. 1452,1469 |
|
~%
1453-97-0 |
| Literature: Helvetica Chimica Acta, , vol. 38, p. 1452,1469 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |