383365-04-6
383365-04-6 structure
- Name: Tenofovir alafenamide
- Chemical Name: 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]-phenoxyphosphinyl]methoxy]propyl]adenine
- CAS Number: 383365-04-6
- Molecular Formula: C21H29N6O5P
- Molecular Weight: 476.466
- Create Date: 2018-07-21 14:09:11
- Modify Date: 2026-06-30 12:57:32
| Name | 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino]-phenoxyphosphinyl]methoxy]propyl]adenine |
|---|---|
| Synonyms |
TAF-IM-A2
9-[(R)-2-[[(R)-[[(S)-1-(isopropoxycarbonyl)ethyl]amino](phenoxy)phosphinyl]methoxy]propyl]adenine Isopropyl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate Tenofovir Alafenamide (R-Phosphine) L-Alanine, N-[(S)-[(1S)-[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester Tenofovir Alafenamide Impurity E Tenofovir Alafenamide Impurity RRS (S)-isopropyl 2-(((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate L-Alanine,N-[(R)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester Tenofovir Alafenamide Impurity 3 N-[(R)-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester Tenofovir Alafenamide Impurity 13 Monomer Tenofovir Alafenamide Impurity 37 (S)-isopropyl 2-(((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)ami Tenofovir related compound enofovir Related Compound 6 Tenofovir Impurity 6-d6 Tenofovir Impurity 48 Tenofovir Impurity 6 Tenofovir Related Compound 6 Isopropyl ((R)-((((R)-1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-l-alaninate 9-[(R)-2-[[(S)-[[(S)-1-(isopropoxycbonyl)ethyl]amino]-phenoxyphosphinyl]methoxy]propyl]adenine TAF Impurity E Tenofovir Alafenamide Diasteromer-1 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 640.4±65.0 °C at 760 mmHg |
| Molecular Formula | C21H29N6O5P |
| Molecular Weight | 476.466 |
| Flash Point | 341.1±34.3 °C |
| Exact Mass | 476.193695 |
| PSA | 153.29000 |
| LogP | 2.20 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.630 |