361189-64-2

361189-64-2 structure

Name: Hydroxy-PEG6-Boc
Chemical Name: tert-butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate
CAS Number: 361189-64-2
Molecular Formula: C₁₉H₃₈O₉
Molecular Weight: 410.50000
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-09-18 18:22:46
Modify Date: 2024-01-14 14:54:05
Hydroxy-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	tert-butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate
Synonyms	hydroxy-peg6-tertbutyl ester Hydroxy-PEG6-t-butly ester

Description	Hydroxy-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562