Hydroxy-PEG6-Boc

Modify Date: 2024-01-14 14:54:05

Hydroxy-PEG6-Boc Structure
Hydroxy-PEG6-Boc structure
Common Name Hydroxy-PEG6-Boc
CAS Number 361189-64-2 Molecular Weight 410.50000
Density 1.068 g/ml Boiling Point N/A
Molecular Formula C19H38O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG6-Boc


Hydroxy-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name tert-butyl 1-hydroxy-3,6,9,12,15,18-hexaoxahenicosan-21-oate
Synonym More Synonyms

 Hydroxy-PEG6-Boc Biological Activity

Description Hydroxy-PEG7-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.068 g/ml
Molecular Formula C19H38O9
Molecular Weight 410.50000
Exact Mass 410.25200
PSA 101.91000
LogP 0.81010

 Synonyms

hydroxy-peg6-tertbutyl ester
Hydroxy-PEG6-t-butly ester
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