136105-89-0

136105-89-0 structure

Name: (Deamino-Cys1,β-(3-pyridyl)-D-Ala2,Arg8)-Vasopressin trifluoroacetate salt
Chemical Name: [deamino-Cys1, D-3-Pyridyl-Ala2, Arg8]-Vasopressin
CAS Number: 136105-89-0
Molecular Formula: C₄₅H₆₃N₁₅O₁₁S₂
Molecular Weight: 1054.21000
Catalog: Signaling Pathways GPCR/G Protein Vasopressin Receptor
Create Date: 2018-12-28 23:39:50
Modify Date: 2024-01-30 13:35:58
Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), is a weak agonist at antidiuretic receptor. However, Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin is a potent agonist at pituitary corticotrope receptor[1].

Name	[deamino-Cys1, D-3-Pyridyl-Ala2, Arg8]-Vasopressin
Synonyms	3-MERCAPTOPROPIONYL-β-3-PYRIDYL-D-ALA-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2

Description	Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), is a weak agonist at antidiuretic receptor. However, Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin is a potent agonist at pituitary corticotrope receptor[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Vasopressin Receptor
Target	Antidiuretic receptor; Pituitary corticotrope receptor[1]
In Vitro	Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin (1 nM-10 μM) 对绵羊离体绵羊垂体前叶细胞有促肾上腺皮质激素释放活性[1]。
In Vivo	Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin (50 μg/sheep; 静脉注射; 单剂量) 显示促肾上腺皮质激素释放活性[1]。
References	[1]. Schwartz J, et al. A potent new synthetic analog of vasopressin with relative agonist specificity for the pituitary. Endocrinology. 1991 Aug;129(2):1107-9.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H332
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn
RIDADR	NONH for all modes of transport