55837-29-1

55837-29-1 structure

55837-29-1 structure

Name: Tiropramide
Chemical Name: N-[3-[4-[2-(diethylamino)ethoxy]phenyl]-1-(dipropylamino)-1-oxopropan-2-yl]benzamide
CAS Number: 55837-29-1
Molecular Formula: C₂₈H₄₁N₃O₃
Molecular Weight: 467.64300
Catalog: Research Areas Others
Create Date: 2018-08-31 18:37:33
Modify Date: 2024-01-03 11:08:03
Tiropramide is an antispasmodic agent that plays important roles in spasmodic pain of the hepatobiliary and urinary tract[1].

Name	N-[3-[4-[2-(diethylamino)ethoxy]phenyl]-1-(dipropylamino)-1-oxopropan-2-yl]benzamide
Synonyms	Tiropramide CR-605 Maiorad

Description	Tiropramide is an antispasmodic agent that plays important roles in spasmodic pain of the hepatobiliary and urinary tract[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Soo Kyoung Baek, et al. Semi-micro high-performance liquid chromatographic analysis of tiropramide in human plasma using column-switching. J Pharm Biomed Anal. 2003 Feb 5;31(1):185-9.

Density	1.06g/cm3
Boiling Point	655ºC at 760 mmHg
Molecular Formula	C₂₈H₄₁N₃O₃
Molecular Weight	467.64300
Flash Point	349.9ºC
Exact Mass	467.31500
PSA	61.88000
LogP	4.78780
Index of Refraction	1.541

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA8325600

CHEMICAL NAME :: Benzenepropanamide, alpha-(benzoylamino)-4-(2-(diethylamino)ethoxy)-N,N-d ipropyl-, (+-)-

CAS REGISTRY NUMBER :: 55837-29-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C28-H41-N3-O3

MOLECULAR WEIGHT :: 467.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,413,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,413,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 430 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,413,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 33900 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4004008

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,413,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,413,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 245 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,413,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 7,413,1982

14325-35-0 structure

14325-35-0

~%

55837-29-1 structure

55837-29-1

Literature: FR2259592DE2503992 , ; Chem.Abstr., , vol. 83, # 193728

60-18-4 structure

60-18-4

~%

55837-29-1 structure

55837-29-1

Literature: FR2259592DE2503992 , ; Chem.Abstr., , vol. 83, # 193728

57227-08-4 structure

57227-08-4

~%

55837-29-1 structure

55837-29-1

Literature: FR2259592DE2503992 , ; Chem.Abstr., , vol. 83, # 193728

57227-09-5 structure

57227-09-5

100-35-6 structure

100-35-6

~%

55837-29-1 structure

55837-29-1

Literature: FR2259592DE2503992 , ; Chem.Abstr., , vol. 83, # 193728

Precursor 5
14325-35-0 60-18-4 57227-08-4 57227-09-5
100-35-6
DownStream 0