73771-04-7
73771-04-7 structure
- Name: Prednicarbate
- Chemical Name: [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate
- CAS Number: 73771-04-7
- Molecular Formula: C27H36O8
- Molecular Weight: 488.570
- Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
- Create Date: 2018-08-28 12:57:09
- Modify Date: 2025-09-12 17:23:27
-
Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis[1][2].
| Name | [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate |
|---|---|
| Synonyms |
(11b)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
(11β)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-3,20-dioxopregna-1,4-dien-21-yl propionate propanoate de 2-{(8S,9S,10R,11S,13S,14S,17R)-17-[(éthoxycarbonyl)oxy]-11-hydroxy-10,13-diméthyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodécahydro-3H-cyclopenta[a]phénanthrén-17-yl}-2-oxoéthyle 11b,17,21-Trihydroxypregna-1,4-diene-3,20-dione 17-(Ethyl Carbonate) 21-Propionate 2-{(8S,9S,10R,11S,13S,14S,17R)-17-[(Ethoxycarbonyl)oxy]-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl}-2-oxoethylpropanoat Dermatop 11β,17,21-Trihydroxypregna-1,4-diene-3,20-dione 17-(ethyl carbonate) 21-propionate 2-{(8S,9S,10R,11S,13S,14S,17R)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl}-2-oxoethyl propanoate (11β)-17-[(ethoxycarbonyl)oxy]-11-hydroxy-3,20-dioxopregna-1,4-dien-21-yl propanoate Carbonic acid, ethyl (11β)-11-hydroxy-3,20-dioxo-21-(1-oxopropoxy)pregna-1,4-dien-17-yl ester Prednicarbate (200 mg) Regemt Prednicarbate HOE-777 S 77 0777 Prednisolone 17-(ethyl carbonate) 21-propionate Regenit Prednitop S-77-0777 Prednisolone 17-Ethylcarbonate 21-Propionate |
| Description | Prednicarbate is a topical corticosteroid agent. Prednicarbate can be used for the research of inflammatory skin diseases, such as atopic dermatitis[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Prednicarbate (0.25%; applied daily to the ear skin area for 2 days) recovers the 2,4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis of mice[2]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 640.7±55.0 °C at 760 mmHg |
| Melting Point | 110 - 112ºC |
| Molecular Formula | C27H36O8 |
| Molecular Weight | 488.570 |
| Flash Point | 209.4±25.0 °C |
| Exact Mass | 488.241028 |
| PSA | 116.20000 |
| LogP | 4.02 |
| Vapour Pressure | 0.0±4.3 mmHg at 25°C |
| Index of Refraction | 1.560 |
| RIDADR | NONH for all modes of transport |
|---|
|
~30%
73771-04-7 |
| Literature: Stache; Fritsch; Rupp; Hitzel; Fehlhaber Arzneimittel-Forschung/Drug Research, 1985 , vol. 35, # 12 p. 1753 - 1757 |
|
~%
73771-04-7 |
| Literature: Arzneimittel-Forschung/Drug Research, , vol. 35, # 12 p. 1753 - 1757 |
|
~%
73771-04-7 |
| Literature: Arzneimittel-Forschung/Drug Research, , vol. 35, # 12 p. 1753 - 1757 |
|
~%
73771-04-7 |
| Literature: Arzneimittel-Forschung/Drug Research, , vol. 35, # 12 p. 1753 - 1757 |
| Precursor 4 | |
|---|---|
| DownStream 2 | |
![[2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate structure](https://image.chemsrc.com/caspic/447/5740-62-5.png)