1431856-99-3

1431856-99-3 structure

Name: Rabacfosadine succinate
Chemical Name: butanedioic acid,ethyl (2S)-2-[[2-[2-amino-6-(cyclopropylamino)purin-9-yl]ethoxymethyl-[[(2S)-1-ethoxy-1-oxopropan-2-yl]amino]phosphoryl]amino]propanoate
CAS Number: 1431856-99-3
Molecular Formula: C₂₅H₄₁N₈O₁₀P
Molecular Weight: 644.61400
Catalog: Research Areas Cancer
Create Date: 2016-01-27 10:51:43
Modify Date: 2024-02-17 23:24:43
Rabacfosadine (GS-9219) succinate, a novel proagent of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells[1].

Name	butanedioic acid,ethyl (2S)-2-[[2-[2-amino-6-(cyclopropylamino)purin-9-yl]ethoxymethyl-[[(2S)-1-ethoxy-1-oxopropan-2-yl]amino]phosphoryl]amino]propanoate
Synonyms	GS-9219 succinate UNII-3L28LG748I L-Alanine,N,N'-(((2-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)ethoxy)methyl)phosphinylidene)bis-,diethyl ester,succinic acid salt (1:1)

Description	Rabacfosadine (GS-9219) succinate, a novel proagent of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Reiser H, et al. GS-9219--a novel acyclic nucleotide analogue withpotent antineoplastic activity in dogs with spontaneous non-Hodgkin's lymphoma.Clin Cancer Res. 2008 May 1;14(9):2824-32. [2]. De Clercq E. Tanovea® for the treatment of lymphoma in dogs. Biochem Pharmacol. 2018 Aug;154:265-269.