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28466-21-9

28466-21-9 structure
28466-21-9 structure
  • Name: 1,3,5-Trimethyl-1H-pyrazol-4-amine
  • Chemical Name: 4-amino-1,3,5-trimethylpyrazole
  • CAS Number: 28466-21-9
  • Molecular Formula: C6H11N3
  • Molecular Weight: 125.172
  • Create Date: 2018-12-25 20:57:15
  • Modify Date: 2024-01-02 15:31:41

Name 4-amino-1,3,5-trimethylpyrazole
Synonyms AKOS PAO-0230
4-Amino-2,3,5-trimethyl-2H-pyrazole
1,3,5-trimethyl-1H-pyrazol-4-ylamine
1H-Pyrazol-4-amine, 1,3,5-trimethyl-
4-Amino-1,3,5-trimethyl-1H-pyrazole
1,3,5-trimethyl-4-aminopyrazole
MFCD00052883
1,3,5-Trimethyl-1H-pyrazol-4-amine
1,3,5-trimethyl-1H-4-aminopyrazole
4-amino-1,3,5-trimethyl-pyrazol
1,3,5-Trimethyl-4-pyrazolamine
Density 1.1±0.1 g/cm3
Boiling Point 236.3±35.0 °C at 760 mmHg
Melting Point 96 °C
Molecular Formula C6H11N3
Molecular Weight 125.172
Flash Point 96.7±25.9 °C
Exact Mass 125.095299
PSA 43.84000
LogP 0.25
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.568
Name: 1 3 5-Trimethyl-1H-pyrazol-4-amine 97% Material Safety Data Sheet
Synonym:
CAS: 28466-21-9
Section 1 - Chemical Product MSDS Name:1 3 5-Trimethyl-1H-pyrazol-4-amine 97% Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
28466-21-9 1,3,5-Trimethyl-1H-pyrazol-4-amine 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 28466-21-9: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: beige
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 101 - 102 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C6H11N3
Molecular Weight: 125

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 28466-21-9: UQ6125100 LD50/LC50:
Not available.
Carcinogenicity:
1,3,5-Trimethyl-1H-pyrazol-4-amine - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 28466-21-9: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 28466-21-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 28466-21-9 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ6125100
CHEMICAL NAME :
Pyrazole, 4-amino-1,3,5-trimethyl-
CAS REGISTRY NUMBER :
28466-21-9
BEILSTEIN REFERENCE NO. :
0110739
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H11-N3
MOLECULAR WEIGHT :
125.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,592,1970
Hazard Codes Xi: Irritant;
Safety Phrases S22-S24/25
RTECS UQ6125100
HS Code 2933199090

~72%

28466-21-9 structure

28466-21-9

Literature: WARNER-LAMBERT COMPANY Patent: EP1203767 A1, 2002 ; Location in patent: Example 39 ;

~78%

28466-21-9 structure

28466-21-9

Literature: Cuadrado, Purificacion; Gonzalez-Nogal, Ana M.; Martinez, Senen Tetrahedron, 1997 , vol. 53, # 25 p. 8585 - 8598

~39%

28466-21-9 structure

28466-21-9

Literature: Cheung, Chi Wai; Surry, David S.; Buchwald, Stephen L. Organic Letters, 2013 , vol. 15, # 14 p. 3734 - 3737

~%

28466-21-9 structure

28466-21-9

Literature: Cuadrado, Purificacion; Gonzalez-Nogal, Ana M.; Martinez, Senen Tetrahedron, 1997 , vol. 53, # 25 p. 8585 - 8598

~%

28466-21-9 structure

28466-21-9

Literature: Musante; Stener Gazzetta Chimica Italiana, 1959 , vol. 89, p. 1579,1594

~%

28466-21-9 structure

28466-21-9

Literature: Musante; Stener Gazzetta Chimica Italiana, 1959 , vol. 89, p. 1579,1594
HS Code 2933199090
Summary 2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%