Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CV 1808
Price: Check
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: 2-Phenylaminoadenosine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: 2-Phenylaminoadenosine
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: (2R,3R,4S,5R)-2-(6-AMINO-2-(PHENYLAMINO)-9H-PURIN-9-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

53296-10-9

53296-10-9 structure

53296-10-9 structure

Name: CV 1808
Chemical Name: 2-Phenylamino Adenosine
CAS Number: 53296-10-9
Molecular Formula: C₁₆H₁₈N₆O₄
Molecular Weight: 358.35
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-09-02 19:13:28
Modify Date: 2025-08-21 12:41:37
CV1808 (2-Phenylaminoadenosine) is a non-selective A2 adenosine receptor (A2 AR) agonist with Kis of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively[1].

Name	2-Phenylamino Adenosine
Synonyms	[3H]-2-Phenylaminoadenosine

Description	CV1808 (2-Phenylaminoadenosine) is a non-selective A2 adenosine receptor (A2 AR) agonist with Kis of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	Human Endogenous Metabolite
In Vitro	CV1808 demonstrates an inhibitory effect on anti-IgE-induced activation at 100 μM[1]. In the presence of Forskolin (1 μM in PC12 cells; 10 μM in Jurkat cells) the EC50 value for CV1808 is 2 μM[2].
In Vivo	Single afferent arterioles of Sprague-Dawley rats are visualized and superfused with solutions containing CV1808 (CV-1808). Superfusion with CV1808 (0.002-2 μM) dilates afferent arterioles[3]. Animal Model: Male Sprague-Dawley rat, weighing 370-410 g[3] Dosage: 0.002, 0.02, 0.2, and 2 μM Administration: Single afferent arterioles of Sprague-Dawley rats were visualized and superfused with solutions containing CV-1808 Result: Afferent arteriolar diameter increased from 17.0±0.3 to 17.2±0.4, 17.8±0.4, 18.5±0.5, and 19.9±0.7 μM, 17.2±2.4% at concentrations of 0.002, 0.02, 0.2, and 2 μM.
References	[1]. K H Yip, et al. Reciprocal modulation of anti-IgE induced histamine release from human mast cells by A₁ and A(2B) adenosine receptors. Br J Pharmacol. 2011 Sep;164(2b):807-19. [2]. I van der Ploeg,et al.Functional characterization of adenosine A2 receptors in Jurkat cells and PC12 cells using adenosine receptor agonists. Naunyn Schmiedebergs Arch Pharmacol.1996 Feb;353(3):250-60. [3]. Ming-Guo Feng, et al. Afferent arteriolar vasodilator effect of adenosine predominantly involves adenosine A2B receptor activation. Am J Physiol Renal Physiol. 2010 Aug;299(2):F310-5.

Density	1.78g/cm3
Boiling Point	766ºC at 760mmHg
Melting Point	210-212ºC
Molecular Formula	C₁₆H₁₈N₆O₄
Molecular Weight	358.35
Flash Point	417.1ºC
Exact Mass	358.13900
PSA	151.57000
LogP	0.41780
Index of Refraction	1.829
Storage condition	−20°C
Water Solubility	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 3.6 mg/mL

WGK Germany	3

Precursor 7
622-34-4 23192-64-5 79715-27-8 622-16-2
53296-13-2 2627-69-2 103-72-0
DownStream 0

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