121264-04-8
121264-04-8 structure
- Name: ICI 204,448 hydrochloride
- Chemical Name: 2-[3-[1-[[2-(3,4-dichlorophenyl)acetyl]-methylamino]-2-pyrrolidin-1-ylethyl]phenoxy]acetic acid,hydrochloride
- CAS Number: 121264-04-8
- Molecular Formula: C23H27Cl3N2O4
- Molecular Weight: 501.83
- Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
- Create Date: 2018-12-22 09:03:50
- Modify Date: 2024-01-15 01:25:47
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ICI-204448 is a κ-opioid agonist with limited access to the CNS, ICI-204448 can displace the binding of the kappa-opioid ligand 3H-bremazocine from guinea pig cerebellum membranes[1].
| Name | 2-[3-[1-[[2-(3,4-dichlorophenyl)acetyl]-methylamino]-2-pyrrolidin-1-ylethyl]phenoxy]acetic acid,hydrochloride |
|---|---|
| Synonyms |
MFCD00153814
ICI 204,448 hydrochloride |
| Description | ICI-204448 is a κ-opioid agonist with limited access to the CNS, ICI-204448 can displace the binding of the kappa-opioid ligand 3H-bremazocine from guinea pig cerebellum membranes[1]. |
|---|---|
| Related Catalog | |
| References |
| Boiling Point | 638.9ºC at 760 mmHg |
|---|---|
| Molecular Formula | C23H27Cl3N2O4 |
| Molecular Weight | 501.83 |
| Flash Point | 340.2ºC |
| Exact Mass | 500.10400 |
| PSA | 70.08000 |
| LogP | 5.03470 |
| Vapour Pressure | 3.39E-17mmHg at 25°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |