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335165-68-9

335165-68-9 structure
335165-68-9 structure
  • Name: Bax channel blocker
  • Chemical Name: 1-(3,6-dibromocarbazol-9-yl)-3-piperazin-1-ylpropan-2-ol,dihydrochloride
  • CAS Number: 335165-68-9
  • Molecular Formula: C19H23Br2Cl2N3O
  • Molecular Weight: 540.11900
  • Catalog: Signaling Pathways Apoptosis Bcl-2 Family
  • Create Date: 2018-12-14 00:13:17
  • Modify Date: 2024-01-02 19:13:52
  • BAI1 is a direct allosteric inhibitor of BAX.

Name 1-(3,6-dibromocarbazol-9-yl)-3-piperazin-1-ylpropan-2-ol,dihydrochloride
Synonyms Bax channel blocker
Description BAI1 is a direct allosteric inhibitor of BAX.
Related Catalog
Target

BAX[1]

References

[1]. Garner TP, et al. Small-molecule allosteric inhibitors of BAX. Nat Chem Biol. 2019 Apr;15(4):322-330.

Boiling Point 388.1ºC at 760 mmHg
Molecular Formula C19H23Br2Cl2N3O
Molecular Weight 540.11900
Flash Point 188.5ºC
Exact Mass 536.95800
PSA 40.43000
LogP 5.45630
Storage condition 2-8℃
HS Code 2933990090

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335165-68-9 structure

335165-68-9

Literature: Applied Research Systems ARS Holding N.V. Patent: EP1094063 A1, 2001 ;

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335165-68-9 structure

335165-68-9

Literature: Applied Research Systems ARS Holding N.V. Patent: EP1094063 A1, 2001 ;

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335165-68-9 structure

335165-68-9

Literature: Bombrun, Agnes; Gerber, Patrick; Casi, Giulio; Terradillos, Olivier; Antonsson, Bruno; Halazy, Serge Journal of Medicinal Chemistry, 2003 , vol. 46, # 21 p. 4365 - 4368

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335165-68-9 structure

335165-68-9

Literature: Bombrun, Agnes; Gerber, Patrick; Casi, Giulio; Terradillos, Olivier; Antonsson, Bruno; Halazy, Serge Journal of Medicinal Chemistry, 2003 , vol. 46, # 21 p. 4365 - 4368

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335165-68-9 structure

335165-68-9

Literature: Bombrun, Agnes; Gerber, Patrick; Casi, Giulio; Terradillos, Olivier; Antonsson, Bruno; Halazy, Serge Journal of Medicinal Chemistry, 2003 , vol. 46, # 21 p. 4365 - 4368
HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%