71963-77-4
71963-77-4 structure
- Name: Artemether
- Chemical Name: artemether
- CAS Number: 71963-77-4
- Molecular Formula: C16H26O5
- Molecular Weight: 298.375
- Catalog: API Antiparasitic drug Antimalarial
- Create Date: 2018-09-03 10:08:30
- Modify Date: 2026-07-01 15:05:44
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Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.Target: AntiparasiticArtemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. Artemether exhibits the highest activity against juvenile stages of the parasites, while adult worms are significantly less susceptible. There was no indication of neurotoxicity following repeated high doses of artemether given fortnightly for up to 5 months. Artemether-integrated with other control strategies-has considerable potential for reducing the current burden of schistosomiasis in different epidemiological settings [1]. There were remarkably inhibitory effects of artmeter on brain glioma growth and angiogenesis in SD rats and the mechanism that artemether inhibited brain glioma growth might be penetrating the blood-brain barrier and inhibiting angiogenesis [2].
| Name | artemether |
|---|---|
| Synonyms |
tesaph
(3R,5aα,8aα,12-Decahydro-10β-methoxy-3,6α,9β-trimethyl-3,12α-oxypyrano[4,3-j]-1,2-benzodioxin temetherr THEMETER WR-254986 5a-beta,6-beta,8a-beta,9-alpha,12-beta,12-(3-alph(+)-ethyl Dihydroqinghaosu Methyl Ether temether [3R-(3R,5aS,6S,8aS,9R,10R,12S,12**)]-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-oxy-12H-pyrano[4,3-j]-1,2-benzodioxin dihydroquinghaosumethylether 3,12-oxy-12h-pyrano(4,3-j)-1,2-benzodioxin,decahydro-10-methoxy-3,6,9-trim Lither temether RS MFCD00866205 temisininelactolmethylether teMether (SM-224) ArteMos Artesaph TEMETHER (3R,5aS,6R,8aS,9R,10S,12R,12-10-Methoxy-3,6,9-trimethyldecahydro-3H-3,12-oxy[1,2]dioxino[4,3-i]isochromene [3r-(3r,5as,6s,8as,9r,10r,12s,12**)]-decahydro-10-methoxy-3,6,9-trimethyl-3,12-oxy-12h-pyrano[4,3-j]-1,2-benzodioxin temether //BP MalteM tMether Larither 13C,2H3]-β-temether TEMTHER temether, 10 mM in DMSO 3,12-oxy-12H-pyrano(4,3-j)-1,2-benzodioxin, decahydro-10-methoxy-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12)-, (+) ArtenaM (1R,4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0.0]hexadecane MalarteM temetherQ: What is temether Q: What is the CAS Number of temether Q: What is the storage condition of temether Q: What e the applications of temether (1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane tesian (3R,5aS,6R,8aS,9R,10S,12R,12-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-oxy-12H-pyrano[4,3-j]-1,2-benzodioxin TEMETHER PH. INT (+)-temether temetherC16H26O5 methyl-dihydrotemisinine (3R,5aS,6R,8aS,9R,10S,12R,12-10-methoxy-3,6,9-trimethyldecahydro-12H-3,12-oxy[1,2]dioxino[4,3-i]isochromene timether 3,12-oxy-12H-pyrano[4,3-j]-1,2-benzodioxin, decahydro-10-methoxy-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12) temether> temether 2015 dihydrotemisininmethylether cgp56696 dihydroqinghaosu methyl ether (3R,5aα,8aα,12-Decahydro-10β-methoxy-3,6α,9β-trimethyl-3β,12α-oxypyrano[4,3-j]-1,2-benzodioxin Decahydro-10-Methoxy-3,6,9-triMethyl-3,12-oxy-12H-pyrano[4,3-j]-1,2-benzodioxin Alpha-temether RS Gvither Artesian teMos temether 71-4 (4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0.0]hexadecane Falcidol SM-224 Dihydrotemisin methyl ether Paluther tenaM α-(N-Methyl-Benzylamino）-3-Hydroxyacetophenone Hydrochloride (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene |
| Description | Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.Target: AntiparasiticArtemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. Artemether exhibits the highest activity against juvenile stages of the parasites, while adult worms are significantly less susceptible. There was no indication of neurotoxicity following repeated high doses of artemether given fortnightly for up to 5 months. Artemether-integrated with other control strategies-has considerable potential for reducing the current burden of schistosomiasis in different epidemiological settings [1]. There were remarkably inhibitory effects of artmeter on brain glioma growth and angiogenesis in SD rats and the mechanism that artemether inhibited brain glioma growth might be penetrating the blood-brain barrier and inhibiting angiogenesis [2]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 357.5±42.0 °C at 760 mmHg |
| Melting Point | 86-89ºC |
| Molecular Formula | C16H26O5 |
| Molecular Weight | 298.375 |
| Flash Point | 140.5±27.8 °C |
| Exact Mass | 298.178009 |
| PSA | 46.15000 |
| LogP | 3.07 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.518 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Codes | Xn |
| Risk Phrases | 22 |
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| RTECS | KD4165000 |
| HS Code | 2932999099 |
| Precursor 8 | |
|---|---|
| DownStream 0 | |
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |