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38915-28-5

38915-28-5 structure

38915-28-5 structure

Name: ICR 340
Chemical Name: Benzo[b][1,5]naphthyridine, 7-chloro-10-[3-[N-(2-chloroethyl)-N-ethyl]aminopropylamino]-2-methoxy-, dihydrochloride
CAS Number: 38915-28-5
Molecular Formula: C₂₀H₂₅Cl₃N₄O
Molecular Weight: 443.79800
Create Date: 2017-06-26 02:43:36
Modify Date: 2025-09-26 16:12:16

Name	Benzo[b][1,5]naphthyridine, 7-chloro-10-[3-[N-(2-chloroethyl)-N-ethyl]aminopropylamino]-2-methoxy-, dihydrochloride

Molecular Formula	C₂₀H₂₅Cl₃N₄O
Molecular Weight	443.79800
Exact Mass	442.10900
PSA	50.28000
LogP	5.68270

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DI2400000

CHEMICAL NAME :: Benzo(b)(1,5)naphthyridine, 7-chloro-10-(3-(N-(2-chloroethyl)-N-ethyl)aminopropyl amino)- 2-methoxy-, dihydrochloride

CAS REGISTRY NUMBER :: 38915-28-5

LAST UPDATED :: 199410

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C20-H24-Cl2-N4-O.2Cl-H

MOLECULAR WEIGHT :: 480.30

WISWESSER LINE NOTATION :: T C666 BN GNJ FO1 IM3N2&2G MG &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD20 - Lethal Dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3737 ug/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4800 ug/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 1 umol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,4875,1979

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